Bioglass/Polylactic Acid Porous Microspheres: Preparation and Their Application as Cell Microcarriers
文献类型：期刊论文
| 作者 | Gao, L; Zhang, ZWB; Chang, J |
| 刊名 | JOURNAL OF INORGANIC MATERIALS
 |
| 出版日期 | 2020-10-20 |
| 期号 | 10页码:1163 |
| ISSN号 | 1000-324X |
| DOI | 10.15541/jim20190593 |
| 文献子类 | Article |
| 英文摘要 | Porous microsphere cell microcarrier with macroporous structure cannot only amplify cells in vitro, but also serve as cell delivery tools to deliver cells to damaged tissues by injection. Bioglass (BG) is an inorganic material with excellent biological activity, however, it is difficult to directly prepare microcarriers with macroporous structure. Therefore, in this study, a BG/poly-lactic acid (PLA) porous microspheres was prepared by double emulsion method. The morphology and structure of the microsphere were characterized by SEM, and the load of BG in the microsphere was characterized by thermo gravimetric analysis and its ion release was detected by ICP. Cell proliferation experiments showed that cells could adhere and grow on the surface and inside of the microspheres. The results show that the microsphere with interconnected open-pore microstructure is suit for cell adhesion and proliferation. Bioglass can promote cell proliferation in the microspheres and the obtained BG/PLA composite microsphere has great potential applications in tissue engineering. |
| WOS关键词 | MESENCHYMAL STEM-CELLS ; BONE REGENERATION ; CARTILAGE ; EXPANSION ; BEADS |
| WOS研究方向 | Materials Science |
| 语种 | 中文 |
| 出版者 | SCIENCE PRESS |
| 源URL | [http://ir.sic.ac.cn/handle/331005/27677]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 推荐引用方式 GB/T 7714 | Gao, L,Zhang, ZWB,Chang, J. Bioglass/Polylactic Acid Porous Microspheres: Preparation and Their Application as Cell Microcarriers[J]. JOURNAL OF INORGANIC MATERIALS,2020(10):1163. |
| APA | Gao, L,Zhang, ZWB,&Chang, J.(2020).Bioglass/Polylactic Acid Porous Microspheres: Preparation and Their Application as Cell Microcarriers.JOURNAL OF INORGANIC MATERIALS(10),1163. |
| MLA | Gao, L,et al."Bioglass/Polylactic Acid Porous Microspheres: Preparation and Their Application as Cell Microcarriers".JOURNAL OF INORGANIC MATERIALS .10(2020):1163. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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