Anthrax Biomarker: a Fluorescent Probe for Dipicolinic Acid Using Eu(III)-doped Nanosheets
文献类型：期刊论文
| 作者 | Wang, B; Wu, Q; Xia, JF; Li, X; Jiang, DY; Li, Q |
| 刊名 | CHINESE JOURNAL OF STRUCTURAL CHEMISTRY
 |
| 出版日期 | 2020-10-15 |
| 期号 | 10页码:1788 |
| ISSN号 | 0254-5861 |
| DOI | 10.14102/j.cnki.0254-5861.2011-2707 |
| 文献子类 | Article |
| 英文摘要 | A novel two-dimensional nanosheet fluorescent probe embedded with rare earth Eu(III) was developed to detect dipicolinic acid (DPA), a biomarker of Bacillus anthracis bacterial spores. DPA, a major component of Bacillus anthracis spores which were highly toxic to humans, was not found in other common bacteria. The ability to detect ultra-low concentrations of DPA would therefore be of great significance. Eu(III)-doped ytterbium hydroxide nanosheets were obtained by mechanical exfoliation from layered rare-earth hydroxide (LRH) materials. The crystallinities, layered structure and morphology of the as-synthesized nanosheets were studied by power X-ray diffraction, transmission electron microscopy and atomic force microscopy. Eu(III) emission increased linearly with DPA addition in the range of 0.1 similar to 30 mu mol/L. Based on the antenna effect, the detection limit of DPA was 0.078 mu mol/L and much lower than the infective dose of Bacillus anthracis in humans of 60 mu mol/L. The nanosheet fluorescent probe exhibited good specificity toward DPA, and the interferences with selected aromatic ligands and amino acids were observed to be negligibly small in comparison with that of DPA. Our findings provide a basis for the application of Eu(III)-doped nanosheets for accurate, sensitive, and selective monitoring of DPA as a biomarker of anthrax. |
| WOS关键词 | COORDINATION POLYMER ; COMPLEXES |
| WOS研究方向 | Chemistry ; Crystallography |
| 语种 | 英语 |
| 出版者 | CHINESE JOURNAL STRUCTURAL CHEMISTRY |
| 源URL | [http://ir.sic.ac.cn/handle/331005/27681]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 推荐引用方式 GB/T 7714 | Wang, B,Wu, Q,Xia, JF,et al. Anthrax Biomarker: a Fluorescent Probe for Dipicolinic Acid Using Eu(III)-doped Nanosheets[J]. CHINESE JOURNAL OF STRUCTURAL CHEMISTRY,2020(10):1788. |
| APA | Wang, B,Wu, Q,Xia, JF,Li, X,Jiang, DY,&Li, Q.(2020).Anthrax Biomarker: a Fluorescent Probe for Dipicolinic Acid Using Eu(III)-doped Nanosheets.CHINESE JOURNAL OF STRUCTURAL CHEMISTRY(10),1788. |
| MLA | Wang, B,et al."Anthrax Biomarker: a Fluorescent Probe for Dipicolinic Acid Using Eu(III)-doped Nanosheets".CHINESE JOURNAL OF STRUCTURAL CHEMISTRY .10(2020):1788. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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