Multifaceted application of nanoparticle-based labeling strategies for stem cell therapy
文献类型：期刊论文
| 作者 | Ma, M; Shu, YM; Tang, YH; Chen, HR |
| 刊名 | NANO TODAY
 |
| 出版日期 | 2020-10-01 |
| ISSN号 | 1748-0132 |
| DOI | 10.1016/j.nantod.2020.100897 |
| 文献子类 | Review |
| 英文摘要 | Stem cell therapy can overcome many unmet clinical challenges that have proven intractable with traditional medicine and treatment strategies because of their strong ability to recover and regenerate injured tissue. Nanoparticle-based labeling agents, in combination with current imaging technologies, have been used to monitor the location, migration, survival, and differentiation of transplanted stem cells in therapeutic processes to fully understand their fates in vivo. In addition, various kinds of functional nanoparticles can exert unique biological effects on stem cells to overcome some problems of current stem cell therapy involving cell homing, survival, retention, and directional differentiation. Moreover, nanoparticle-based theranostic labeling, in which both imaging and treatment modalities are delivered with the stem cells, has emerged as a new strategy to enhance the therapeutic effect of stem cells and shows great potential for future stem cell therapy. The aim of this review is to describe the current roles played by nanoparticles in cell tracking, cell fate regulation, and theranostic labeling in stem cell therapy. Important issues and perspectives on the potential growth of this area are also critically discussed. (C) 2020 Elsevier Ltd. All rights reserved. |
| WOS关键词 | MESOPOROUS SILICA NANOPARTICLES ; IRON-OXIDE NANOPARTICLES ; MRI CONTRAST AGENTS ; PROMOTE OSTEOGENIC DIFFERENTIATION ; AGGREGATION-INDUCED EMISSION ; LONG-TERM TRACKING ; IN-VIVO ; SILVER NANOPARTICLES ; GOLD NANOPARTICLES ; QUANTUM DOTS |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://ir.sic.ac.cn/handle/331005/27708]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 推荐引用方式 GB/T 7714 | Ma, M,Shu, YM,Tang, YH,et al. Multifaceted application of nanoparticle-based labeling strategies for stem cell therapy[J]. NANO TODAY,2020. |
| APA | Ma, M,Shu, YM,Tang, YH,&Chen, HR.(2020).Multifaceted application of nanoparticle-based labeling strategies for stem cell therapy.NANO TODAY. |
| MLA | Ma, M,et al."Multifaceted application of nanoparticle-based labeling strategies for stem cell therapy".NANO TODAY (2020). |
入库方式： OAI收割
来源：上海硅酸盐研究所
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