Preparation and characteristics of a novel oxygen-releasing coating for improved cell responses in hypoxic environment
文献类型：期刊论文
| 作者 | Jiang, YY; Xie, YT; Chen, ZM; Li, K; Zheng, XB |
| 刊名 | JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
 |
| 出版日期 | 2020-07-20 |
| ISSN号 | 1549-3296 |
| DOI | 10.1002/jbm.a.37020 |
| 文献子类 | Article; Early Access |
| 英文摘要 | Affected by environmental factors such as oxygen deficiency, the secretion of growth factor was abnormal in bone injury sites, resulting in the poor responses of osteoblasts and prolonging the healing process. Herein, in this study, we reported an in situ oxygen-releasing porous titanium coating that combines the dual degradability of poly(lactic-co-glycolic acid) with the self-releasing oxygen capacity of the CaO(2)core. The resulting formulation exhibited stable oxygen-releasing capacity as well as the ability to promote proliferation and differentiation of the MC3T3 cell line under hypoxia conditions. According to these results, oxygen-releasing coatings based on improved cellular microenvironment may be a promising bone repair material that would reduce the incidence of difficult bone healing in the future. |
| WOS关键词 | KEY ROLE ; TITANIUM ; DIFFERENTIATION ; ANGIOGENESIS ; FRACTURE ; COLLAGEN ; SURFACE ; PLGA ; VEGF ; IMMOBILIZATION |
| WOS研究方向 | Engineering ; Materials Science |
| 语种 | 英语 |
| 出版者 | WILEY |
| 源URL | [http://ir.sic.ac.cn/handle/331005/27901]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 推荐引用方式 GB/T 7714 | Jiang, YY,Xie, YT,Chen, ZM,et al. Preparation and characteristics of a novel oxygen-releasing coating for improved cell responses in hypoxic environment[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,2020. |
| APA | Jiang, YY,Xie, YT,Chen, ZM,Li, K,&Zheng, XB.(2020).Preparation and characteristics of a novel oxygen-releasing coating for improved cell responses in hypoxic environment.JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A. |
| MLA | Jiang, YY,et al."Preparation and characteristics of a novel oxygen-releasing coating for improved cell responses in hypoxic environment".JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2020). |
入库方式： OAI收割
来源：上海硅酸盐研究所
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