Energy Conversion-Based Nanotherapy for Rheumatoid Arthritis Treatment
文献类型：期刊论文
| 作者 | Wang, PP; Li, A; Yu, LD; Chen, Y; Xu, D |
| 刊名 | FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
 |
| 出版日期 | 2020-07-10 |
| ISSN号 | 2296-4185 |
| DOI | 10.3389/fbioe.2020.00652 |
| 文献子类 | Review |
| 英文摘要 | Rheumatoid arthritis (RA) is characterized by synovial hyperplasia and cartilage/bone destruction, which results in a high disability rate on human health and a huge burden on social economy. At present, traditional therapies based on drug therapy still cannot cure RA, in accompany with the potential serious side effects. Based on the development of nanobiotechnology and nanomedicine, energy conversion-based nanotherapy has demonstrated distinctive potential and performance in RA treatment. This strategy employs specific nanoparticles with intrinsic physiochemical properties to target lesions with the following activation by diverse external stimuli, such as light, ultrasound, microwave, and radiation. These nanoagents subsequently produce therapeutic effects or release therapeutic factors to promote necrotic apoptosis of RA inflammatory cells, reduce the concentration of related inflammatory factors, relieve the symptoms of RA, which are expected to ultimately improve the life quality of RA patients. This review highlights and discusses the versatile biomedical applications of energy conversion-based nanotherapy in efficient RA treatment, in together with the deep clarification of the facing challenges and further prospects on the final clinical translations of these energy conversion-based nanotherapies against RA. |
| WOS关键词 | DRUG-DELIVERY SYSTEMS ; SONODYNAMIC THERAPY ; PHOTODYNAMIC TREATMENT ; PHOTOTHERMAL THERAPY ; HYALURONIC-ACID ; NANOPARTICLES ; METHOTREXATE ; PATHOGENESIS ; OXYGEN ; MECHANISM |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Science & Technology - Other Topics |
| 语种 | 英语 |
| 出版者 | FRONTIERS MEDIA SA |
| 源URL | [http://ir.sic.ac.cn/handle/331005/27910]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 推荐引用方式 GB/T 7714 | Wang, PP,Li, A,Yu, LD,et al. Energy Conversion-Based Nanotherapy for Rheumatoid Arthritis Treatment[J]. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY,2020. |
| APA | Wang, PP,Li, A,Yu, LD,Chen, Y,&Xu, D.(2020).Energy Conversion-Based Nanotherapy for Rheumatoid Arthritis Treatment.FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. |
| MLA | Wang, PP,et al."Energy Conversion-Based Nanotherapy for Rheumatoid Arthritis Treatment".FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020). |
入库方式： OAI收割
来源：上海硅酸盐研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。