A selective and sensitive fluorescent probe for bilirubin in human serum based on europium(III) post-functionalized Zr(IV)-Based MOFs
文献类型：期刊论文
| 作者 | Xia, C; Xu, Y; Cao, MM; Liu, YP; Xia, JF; Jiang, DY; Zhou, GH; Xie, RJ; Zhang, DF; Li, HL |
| 刊名 | TALANTA
 |
| 出版日期 | 2020-05-15 |
| ISSN号 | 0039-9140 |
| DOI | 10.1016/j.talanta.2020.120795 |
| 文献子类 | Article |
| 英文摘要 | In the present study, a kind of Eu(III) post-functionalized Zr(IV)-based metal-organic framework (UiO-66(COOH)(2), Zr-MOF: Eu3+) was synthesized and utilized as an independently luminescent probe for sensing bilirubin (BR) in human serum, a biomarker of jaundice hepatitis. It can be served as a turn-off fluorescent switch for BR because its red emission from Eu3+ can be easily quenched by BR through a fluorescent resonant energy transfer (FRET) process between BR and its ligands, and as a result, BR is recognized successfully. Particularly, Zr-MOF: Eu3+ has shown many appealing properties, such as high sensitivity, quick response (less than 1 min), broad response window (0-15 mu M), and excellent selectivity. Most importantly, a kind of portable test paper based on Zr-MOF: Eu3+ probe has been developed for directly assessing the level of BR in real human serum and further diagnosing bilirubin-related diseases via visually observing the luminescent color variation. |
| WOS关键词 | METAL-ORGANIC FRAMEWORK ; GOLD NANOCLUSTERS ; CARBON DOTS ; SENSOR ; FRET ; EMISSION ; DEFECTS ; CENTERS ; UIO-66 ; OXIDE |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ELSEVIER |
| 源URL | [http://ir.sic.ac.cn/handle/331005/28067]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 推荐引用方式 GB/T 7714 | Xia, C,Xu, Y,Cao, MM,et al. A selective and sensitive fluorescent probe for bilirubin in human serum based on europium(III) post-functionalized Zr(IV)-Based MOFs[J]. TALANTA,2020. |
| APA | Xia, C.,Xu, Y.,Cao, MM.,Liu, YP.,Xia, JF.,...&Li, HL.(2020).A selective and sensitive fluorescent probe for bilirubin in human serum based on europium(III) post-functionalized Zr(IV)-Based MOFs.TALANTA. |
| MLA | Xia, C,et al."A selective and sensitive fluorescent probe for bilirubin in human serum based on europium(III) post-functionalized Zr(IV)-Based MOFs".TALANTA (2020). |
入库方式： OAI收割
来源：上海硅酸盐研究所
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