A rank-based approach to estimating monotone individualized two treatment regimes
文献类型：期刊论文
| 作者 | Zhang, Haixiang1; Huang, Jian4; Sun, Liuquan2,3
|
| 刊名 | COMPUTATIONAL STATISTICS & DATA ANALYSIS
 |
| 出版日期 | 2020-11-01 |
| 卷号 | 151页码:12 |
| 关键词 | Generalized regression Individualized treatment rule Outlier Personalized medicine Rank correlation |
| ISSN号 | 0167-9473 |
| DOI | 10.1016/j.csda.2020.107015 |
| 英文摘要 | Developing effective individualized treatment rules (ITRs) for diseases is an important goal of clinical research. Much effort has been devoted to estimating individualized treatment effects in the recent literature. However, there have not been systematic studies on the robust inference for individualized treatment effects when there exist potential outliers. We propose a monotone ITR in the framework of a semiparametric generalized regression with two treatments and estimate the treatment effects via a smoothed maximum rank correlation procedure. We provide sufficient conditions under which the proposed estimator has an asymptotically normal distribution whose variance can be consistently estimated based on a resampling procedure. We evaluate the finite-sample properties of our proposed approach via simulation studies. We also illustrate the proposed method by applying it to a data set from an AIDS clinical trials study. (C) 2020 Elsevier B.V. All rights reserved. |
| 资助项目 | National Science Foundation of USA[DMS-1916199] ; National Natural Science Foundation of China[11771431] ; National Natural Science Foundation of China[11690015] ; National Natural Science Foundation of China[11926341] ; Key Laboratory of RCSDS, CAS, China[2008DP173182] |
| WOS研究方向 | Computer Science ; Mathematics |
| 语种 | 英语 |
| WOS记录号 | WOS:000542951600009 |
| 出版者 | ELSEVIER |
| 源URL | [http://ir.amss.ac.cn/handle/2S8OKBNM/51666]  |
| 专题 | 应用数学研究所 |
| 通讯作者 | Zhang, Haixiang |
| 作者单位 | 1.Tianjin Univ, Ctr Appl Math, Tianjin 300072, Peoples R China 2.Guangzhou Univ, Sch Econ & Stat, Guangzhou 510006, Peoples R China 3.Chinese Acad Sci, Acad Math & Syst Sci, Beijing 100190, Peoples R China 4.Univ Iowa, Dept Stat & Actuarial Sci, Iowa City, IA 52242 USA |
| 推荐引用方式 GB/T 7714 | Zhang, Haixiang,Huang, Jian,Sun, Liuquan. A rank-based approach to estimating monotone individualized two treatment regimes[J]. COMPUTATIONAL STATISTICS & DATA ANALYSIS,2020,151:12. |
| APA | Zhang, Haixiang,Huang, Jian,&Sun, Liuquan.(2020).A rank-based approach to estimating monotone individualized two treatment regimes.COMPUTATIONAL STATISTICS & DATA ANALYSIS,151,12. |
| MLA | Zhang, Haixiang,et al."A rank-based approach to estimating monotone individualized two treatment regimes".COMPUTATIONAL STATISTICS & DATA ANALYSIS 151(2020):12. |
入库方式： OAI收割
来源：数学与系统科学研究院
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