Nonparametric estimation of distributions and diagnostic accuracy based on group-tested results with differential misclassification
文献类型：期刊论文
| 作者 | Zhang, Wei3 ; Liu, Aiyi2; Li, Qizhai3; Albert, Paul S.1
|
| 刊名 | BIOMETRICS
 |
| 出版日期 | 2020-03-05 |
| 页码 | 10 |
| 关键词 | coverage probability diagnostic accuracy differential misclassification group testing integrated absolute bias integrated mean squared error rare disease ROC curves |
| ISSN号 | 0006-341X |
| DOI | 10.1111/biom.13236 |
| 英文摘要 | This article concerns the problem of estimating a continuous distribution in a diseased or nondiseased population when only group-based test results on the disease status are available. The problem is challenging in that individual disease statuses are not observed and testing results are often subject to misclassification, with further complication that the misclassification may be differential as the group size and the number of the diseased individuals in the group vary. We propose a method to construct nonparametric estimation of the distribution and obtain its asymptotic properties. The performance of the distribution estimator is evaluated under various design considerations concerning group sizes and classification errors. The method is exemplified with data from the National Health and Nutrition Examination Survey study to estimate the distribution and diagnostic accuracy of C-reactive protein in blood samples in predicting chlamydia incidence. |
| 资助项目 | Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) ; Beijing Natural Science Foundation[Z180006] ; National Nature Science Foundation of China[11722113] ; Intramural Research Program of theNational Cancer Institute (NCI) |
| WOS研究方向 | Life Sciences & Biomedicine - Other Topics ; Mathematical & Computational Biology ; Mathematics |
| 语种 | 英语 |
| WOS记录号 | WOS:000560958200001 |
| 出版者 | WILEY |
| 源URL | [http://ir.amss.ac.cn/handle/2S8OKBNM/52039]  |
| 专题 | 系统科学研究所 |
| 通讯作者 | Liu, Aiyi |
| 作者单位 | 1.NCI, Biostat Branch, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA 2.Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Biostat & Bioinformat Branch, NIH, Bethesda, MD 20892 USA 3.Chinese Acad Sci, Acad Math & Syst Sci, NCMIS, LSC, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Wei,Liu, Aiyi,Li, Qizhai,et al. Nonparametric estimation of distributions and diagnostic accuracy based on group-tested results with differential misclassification[J]. BIOMETRICS,2020:10. |
| APA | Zhang, Wei,Liu, Aiyi,Li, Qizhai,&Albert, Paul S..(2020).Nonparametric estimation of distributions and diagnostic accuracy based on group-tested results with differential misclassification.BIOMETRICS,10. |
| MLA | Zhang, Wei,et al."Nonparametric estimation of distributions and diagnostic accuracy based on group-tested results with differential misclassification".BIOMETRICS (2020):10. |
入库方式： OAI收割
来源：数学与系统科学研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。