3-Aminooxetanes: versatile 1,3-amphoteric molecules for intermolecular annulation reactions
文献类型：期刊论文
| 作者 | Lai, Zengwei1,2; Zhang, Renwei1; Feng, Qiang1; Sun, Jianwei1 |
| 刊名 | CHEMICAL SCIENCE
 |
| 出版日期 | 2020-09-28 |
| 卷号 | 11期号:36页码:9945-9949 |
| ISSN号 | 2041-6520 |
| DOI | 10.1039/d0sc04254d |
| 通讯作者 | Sun, Jianwei(sunjw@ust.hk) |
| 英文摘要 | Despite the versatility of amphoteric molecules, stable and easily accessible ones are still limitedly known. As a result, the discovery of new amphoteric reactivity remains highly desirable. Herein we introduce 3-aminooxetanes as a new family of stable and readily available 1,3-amphoteric molecules and systematically demonstrated their amphoteric reactivity toward polarized pi-systems in a diverse range of intermolecular [3 + 2] annulations. These reactions not only enrich the reactivity of oxetanes, but also provide convergent access to valuable heterocycles. |
| WOS关键词 | RING-OPENING REACTIONS ; N-ACYL ENAMINES ; AMPHOTERIC MOLECULES ; FACILE SYNTHESIS ; VINYL OXETANES ; HETEROCYCLES ; DERIVATIVES ; EXPANSION ; ALDEHYDES ; ACCESS |
| 资助项目 | NSFC[21572192] ; NSFC[81703341] ; NSFC[91956114] ; Hong Kong RGC[16302318] ; Hong Kong RGC[16302617] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000572262400018 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/291278]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Sun, Jianwei |
| 作者单位 | 1.Hong Kong Univ Sci & Technol, Shenzhen Res Inst, Dept Chem, Kowloon, Clear Water Bay, Hong Kong, Peoples R China 2.Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lai, Zengwei,Zhang, Renwei,Feng, Qiang,et al. 3-Aminooxetanes: versatile 1,3-amphoteric molecules for intermolecular annulation reactions[J]. CHEMICAL SCIENCE,2020,11(36):9945-9949. |
| APA | Lai, Zengwei,Zhang, Renwei,Feng, Qiang,&Sun, Jianwei.(2020).3-Aminooxetanes: versatile 1,3-amphoteric molecules for intermolecular annulation reactions.CHEMICAL SCIENCE,11(36),9945-9949. |
| MLA | Lai, Zengwei,et al."3-Aminooxetanes: versatile 1,3-amphoteric molecules for intermolecular annulation reactions".CHEMICAL SCIENCE 11.36(2020):9945-9949. |
入库方式： OAI收割
来源：上海药物研究所
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