Copper-mediated C-H thiolation of (hetero)arenes using weakly coordinating directing group
文献类型：期刊论文
| 作者 | Wu, Peng1; Cheng, Tai-Jin2,4; Lin, Hai-Xia1; Xu, Hui2; Dai, Hui-Xiong2,3,4
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| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2020-07-09 |
| 卷号 | 61期号:28页码:4 |
| 关键词 | Copper catalyst C-H activation Weakly coordinating directing group Thiolation |
| ISSN号 | 0040-4039 |
| DOI | 10.1016/j.tetlet.2020.152062 |
| 通讯作者 | Dai, Hui-Xiong(hxdai@simm.ac.cn) |
| 英文摘要 | We have developed a copper-mediated C-H thiolation of (hetero)arenes by using monodentate amide as weakly coordinating directing group. This protocol features excellent functional group tolerance and shows satisfactory compatibility with various heterocycles, such as indole, pyrrole, imidazole, pyridine, thiophene and quinoline. The robust nature of this protocol renders that it has potential value in the synthetic application. (C) 2020 Elsevier Ltd. All rights reserved. |
| WOS关键词 | SULFENYLATION ; BONDS ; FUNCTIONALIZATIONS ; CHALCOGENATION ; DISULFIDES ; ACTIVATION ; AXITINIB ; ACCESS ; LIGAND |
| 资助项目 | Shanghai Institute of Materia Medica ; Chinese Academy of Sciences ; National Natural Science Foundation of China[21772211] ; Youth Innovation Promotion Association CAS[2014229] ; Youth Innovation Promotion Association CAS[2018293] ; Institutes for Drug Discovery and Development, Chinese Academy of Sciences[CASIMM0120163006] ; Science and Technology Commission of Shanghai Municipality[17JC1405000] ; Program of Shanghai Academic Research Leader[19XD1424600] ; National Science & Technology Major Project ``Key New Drug Creation and Manufacturing Program, China[2018ZX09711002-006] ; State Key Laboratory of Natural and Biomimetic Drugs |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000543324700003 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/291762]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Dai, Hui-Xiong |
| 作者单位 | 1.Shanghai Univ, Innovat Drug Res Ctr, Dept Chem, 99 Shangda Rd, Shanghai 200444, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, Shanghai 201203, Peoples R China 3.Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Peng,Cheng, Tai-Jin,Lin, Hai-Xia,et al. Copper-mediated C-H thiolation of (hetero)arenes using weakly coordinating directing group[J]. TETRAHEDRON LETTERS,2020,61(28):4. |
| APA | Wu, Peng,Cheng, Tai-Jin,Lin, Hai-Xia,Xu, Hui,&Dai, Hui-Xiong.(2020).Copper-mediated C-H thiolation of (hetero)arenes using weakly coordinating directing group.TETRAHEDRON LETTERS,61(28),4. |
| MLA | Wu, Peng,et al."Copper-mediated C-H thiolation of (hetero)arenes using weakly coordinating directing group".TETRAHEDRON LETTERS 61.28(2020):4. |
入库方式： OAI收割
来源：上海药物研究所
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