A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions
文献类型：期刊论文
| 作者 | Xue, Kangsheng5; Sun, Guoxiang4; Zhang, Yanzhi3; Chen, Xubing3; Zhou, Yang1,2; Hou, Jinjun1,2 ; Long, Huali1,2; Zhang, Zijia1,2; Lei, Min1,2; Wu, Wanying1,2
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| 刊名 | SYNTHETIC COMMUNICATIONS
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| 出版日期 | 2020-11-19 |
| 页码 | 10 |
| 关键词 | Aldehyde chalcone Claisen-Schmidt reaction ketone PPh3 I2 |
| ISSN号 | 0039-7911 |
| DOI | 10.1080/00397911.2020.1847295 |
| 通讯作者 | Lei, Min(mlei@simm.ac.cn) ; Wu, Wanying(wanyingwu@simm.ac.cn) |
| 英文摘要 | A straightforward and general method has been developed for the synthesis of chalcone derivatives by a Claisen-Schmidt reaction in the presence of PPh3/I-2 in 1,4-dioxane under reflux temperatures. With the condensation of the aromatic ketone and aldehyde occurring at non-strongly alkaline conditions, our proposed method significantly expands the range of applicable substrates, especially for groups that are unstable under alkaline conditions. |
| WOS关键词 | SOLVENT-FREE CONDITIONS ; EFFICIENT SYNTHESIS ; HETEROGENEOUS CATALYST ; BIOLOGICAL EVALUATION ; ALDOL CONDENSATIONS ; DESIGN ; AGENTS ; FLAVONOIDS ; INHIBITORS ; AMIDATION |
| 资助项目 | Special Fund for Strategic Pilot Technology of the Chinese Academy of Sciences[XDA12020379] ; National Natural Science Foundation of China[81973455] ; National Key R&D Program of China[2018YFC1707900] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000590637100001 |
| 出版者 | TAYLOR & FRANCIS INC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/292692]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Lei, Min; Wu, Wanying |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing, Peoples R China 2.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, Natl Engn Lab TCM Standardizat Technol, Shanghai, Peoples R China 3.Dali Univ, Coll Pharm, Dali, Peoples R China 4.Yancheng Inst Technol, Sch Chem & Chem Engn, Yancheng, Jiangsu, Peoples R China 5.Changchun Univ Chinese Med, Coll Pharm, Changchun, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xue, Kangsheng,Sun, Guoxiang,Zhang, Yanzhi,et al. A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions[J]. SYNTHETIC COMMUNICATIONS,2020:10. |
| APA | Xue, Kangsheng.,Sun, Guoxiang.,Zhang, Yanzhi.,Chen, Xubing.,Zhou, Yang.,...&Wu, Wanying.(2020).A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions.SYNTHETIC COMMUNICATIONS,10. |
| MLA | Xue, Kangsheng,et al."A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions".SYNTHETIC COMMUNICATIONS (2020):10. |
入库方式： OAI收割
来源：上海药物研究所
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