Influence of physical properties of carrier on the performance of dry powder inhalers
文献类型：期刊论文
| 作者 | Peng Tingting2; Lin Shiqi2; Niu Boyi2; Wang Xinyi2; Huang Ying2; Zhang Xuejuan2; Li Ge2; Pan Xin2; Wu Chuanbin2 |
| 刊名 | Acta Pharmaceutica Sinica B
 |
| 出版日期 | 2016 |
| 卷号 | 6期号:4页码:308 |
| 关键词 | Carrier Particle size Morphology Surface roughness Performance Dry powder inhaler Therapeutics. Pharmacology RM1-950 |
| ISSN号 | 2211-3835 |
| 英文摘要 | Dry powder inhalers (DPIs) offer distinct advantages as a means of pulmonary drug delivery and have attracted much attention in the field of pharmaceutical science. DPIs commonly contain micronized drug particles which, because of their cohesiveness and strong propensity to aggregate, have poor aerosolization performance. Thus carriers with a larger particle size are added to address this problem. However, the performance of DPIs is profoundly influenced by the physical properties of the carrier, particularly their particle size, morphology/shape and surface roughness. Because these factors are interdependent, it is difficult to completely understand how they individually influence DPI performance. The purpose of this review is to summarize and illuminate how these factors affect drug–carrier interaction and influence the performance of DPIs. |
| 资助项目 | [Pearl River S&T Nova Program of Guangzhou] |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/292830]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.中国科学院上海药物研究所 2.中国科学院广州地球化学研究所 |
| 推荐引用方式 GB/T 7714 | Peng Tingting,Lin Shiqi,Niu Boyi,et al. Influence of physical properties of carrier on the performance of dry powder inhalers[J]. Acta Pharmaceutica Sinica B,2016,6(4):308. |
| APA | Peng Tingting.,Lin Shiqi.,Niu Boyi.,Wang Xinyi.,Huang Ying.,...&Wu Chuanbin.(2016).Influence of physical properties of carrier on the performance of dry powder inhalers.Acta Pharmaceutica Sinica B,6(4),308. |
| MLA | Peng Tingting,et al."Influence of physical properties of carrier on the performance of dry powder inhalers".Acta Pharmaceutica Sinica B 6.4(2016):308. |
入库方式： OAI收割
来源：上海药物研究所
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