Two new cassane diterpenoids from the seeds of Caesalpinia sappan Linn.
文献类型：期刊论文
| 作者 | Zhang JingYu; Wu FeiHua; Qu Wei; Liang JingYu |
| 刊名 | CHINESE JOURNAL OF NATURAL MEDICINES
 |
| 出版日期 | 2012 |
| 卷号 | 10期号:3页码:218 |
| 关键词 | IN-VITRO BRAZILIN Caesalpinia sappan Cassane-type furanoditerpenes Cytotoxicity Phanginin L Phanginin M |
| ISSN号 | 1672-3651 |
| 英文摘要 | AIM: To study the chemical components of the seeds of Caesalpinia sappan. METHODS: Compounds were isolated and purified by column chromatography. Their structures were elucidated on the basis of spectroscopic methods. In addition, the cytotoxic activity of these compounds were evaluated using SF-268, MCF-7 and HepG2 cell lines by the MTT assay. RESULTS: Four cassane diterpenoids were obtained and their structures were identified as phanginin L (1), phanginin M (2), phanginin I (3), phanginin G (4). CONCLUSION: Phanginin L (1) and phanginin M (2) are new cassane diterpenoids. Compound 1 showed moderate cytotoxicity against HepG2 cell line with IC50 of 9.13 mu g.mL(-1). |
| 资助项目 | [Postgraduate Innovation Project of Jiangsu Province, China] |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/293716]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | Zhang JingYu,Wu FeiHua,Qu Wei,et al. Two new cassane diterpenoids from the seeds of Caesalpinia sappan Linn.[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2012,10(3):218. |
| APA | Zhang JingYu,Wu FeiHua,Qu Wei,&Liang JingYu.(2012).Two new cassane diterpenoids from the seeds of Caesalpinia sappan Linn..CHINESE JOURNAL OF NATURAL MEDICINES,10(3),218. |
| MLA | Zhang JingYu,et al."Two new cassane diterpenoids from the seeds of Caesalpinia sappan Linn.".CHINESE JOURNAL OF NATURAL MEDICINES 10.3(2012):218. |
入库方式： OAI收割
来源：上海药物研究所
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