Novel glycine-dependent inactivation of NMDA receptors in cultured hippocampal neurons
文献类型:期刊论文
作者 | Zhang YunFeng2; Li Xia2; Peng LiangLiang2; Wang GuoHua2; Ke KaiFu1; Jiang ZhengLin2 |
刊名 | NEUROSCIENCE BULLETIN
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出版日期 | 2012 |
卷号 | 28期号:5页码:550 |
关键词 | MOLECULAR DETERMINANTS INTERNALIZATION MODULATION CHANNELS SUBUNIT glycine N-methyl-D-aspartate receptors calcium imaging NMDA-NR1 subunit hippocampal neurons inactivation |
ISSN号 | 1673-7067 |
英文摘要 | Glycine acts as a co-agonist for the activation of N-methyl-D-aspartate receptors (NMDARs) by binding to glycine sites, thus potentiating glutamate-elicited responses and inhibiting NMDAR desensitization in a dose-dependent manner. The present study aimed to characterize the glycine-dependent inactivation of NMDARs and to explore its pathophysiological significance. |
资助项目 | [Priority Academic Program Development of Jiangsu Higher Education Institutions] |
语种 | 英语 |
源URL | [http://119.78.100.183/handle/2S10ELR8/293740] ![]() |
专题 | 中国科学院上海药物研究所 |
作者单位 | 1.南通大学 2.中国科学院上海药物研究所 |
推荐引用方式 GB/T 7714 | Zhang YunFeng,Li Xia,Peng LiangLiang,et al. Novel glycine-dependent inactivation of NMDA receptors in cultured hippocampal neurons[J]. NEUROSCIENCE BULLETIN,2012,28(5):550. |
APA | Zhang YunFeng,Li Xia,Peng LiangLiang,Wang GuoHua,Ke KaiFu,&Jiang ZhengLin.(2012).Novel glycine-dependent inactivation of NMDA receptors in cultured hippocampal neurons.NEUROSCIENCE BULLETIN,28(5),550. |
MLA | Zhang YunFeng,et al."Novel glycine-dependent inactivation of NMDA receptors in cultured hippocampal neurons".NEUROSCIENCE BULLETIN 28.5(2012):550. |
入库方式: OAI收割
来源:上海药物研究所
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