Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats
文献类型：期刊论文
| 作者 | Liu Li2; Miao Mingxing1; Zhong Zeyu2; Xu Ping2; Chen Yang2; Liu Xiaodong2 |
| 刊名 | ACTA PHARMACOLOGICA SINICA
 |
| 出版日期 | 2016 |
| 卷号 | 37期号:4页码:561 |
| 关键词 | VIVO ANTIBACTERIAL ACTIVITIES DRUG-DRUG INTERACTIONS HUMAN LIVER-MICROSOMES IN-VIVO CYTOCHROME-P450 ENZYMES HEALTHY-VOLUNTEERS COCKTAIL APPROACH METABOLISM QUINOLONE CS-940 caderofloxacin cocktail approach chlorzoxazone CYP2E1 pharmacokinetics drug-drug interaction |
| ISSN号 | 1671-4083 |
| 英文摘要 | Aim: Caderofloxacin is a new fluoroquinolone that is under phase III clinical trials in China. Here we examined the effects of caderofloxacin on rat hepatic cytochrome P450 (CYP450) isoforms as well as the potential of caderofloxacin interacting with co-administered drugs. |
| 资助项目 | [National Natural Science Foundation of China] ; [Fundamental Research Funds for the Central Universities] ; [Priority Academic Program for Development of the Jiangsu Higher Education Institutions] |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/294802]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.中国科学院南京地理与湖泊研究所 2.中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | Liu Li,Miao Mingxing,Zhong Zeyu,et al. Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats[J]. ACTA PHARMACOLOGICA SINICA,2016,37(4):561. |
| APA | Liu Li,Miao Mingxing,Zhong Zeyu,Xu Ping,Chen Yang,&Liu Xiaodong.(2016).Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats.ACTA PHARMACOLOGICA SINICA,37(4),561. |
| MLA | Liu Li,et al."Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats".ACTA PHARMACOLOGICA SINICA 37.4(2016):561. |
入库方式： OAI收割
来源：上海药物研究所
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