Small molecule inhibitors of amyloid β peptide aggregation as a potential therapeutic strategy for Alzheimer＇s disease
文献类型：期刊论文
| 作者 | Nie Qin2; Du Xiaoguang1; Geng Meiyu2 |
| 刊名 | 中国药理学报：英文版
 |
| 出版日期 | 2011 |
| 卷号 | 32.0期号:005页码:545 |
| 关键词 | 阿尔茨海默氏病 淀粉样蛋白 小分子 抑制剂 肽 治疗 合作 病理过程 |
| ISSN号 | 1671-4083 |
| 英文摘要 | Amyloid β （Aβ） peptides have long been viewed as a potential target for Alzheimer＇s disease （AD）. Aggregation of Aβ peptides in the brain tissue is believed to be an exclusively pathological process. Therefore, blocking the initial stages of Aβ peptide aggregation with small molecules could hold considerable promise as the starting point for the development of new therapies for AD. Recent rapid progresses in our understanding of toxic amyloid assembly provide a fresh impetus for this interesting approach. Here, we discuss the problems, challenges and new concepts in targeting Aβ peptides. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/294962]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.中国科学院上海药物研究所 2.中国海洋大学 |
| 推荐引用方式 GB/T 7714 | Nie Qin,Du Xiaoguang,Geng Meiyu. Small molecule inhibitors of amyloid β peptide aggregation as a potential therapeutic strategy for Alzheimer＇s disease[J]. 中国药理学报：英文版,2011,32.0(005):545. |
| APA | Nie Qin,Du Xiaoguang,&Geng Meiyu.(2011).Small molecule inhibitors of amyloid β peptide aggregation as a potential therapeutic strategy for Alzheimer＇s disease.中国药理学报：英文版,32.0(005),545. |
| MLA | Nie Qin,et al."Small molecule inhibitors of amyloid β peptide aggregation as a potential therapeutic strategy for Alzheimer＇s disease".中国药理学报：英文版 32.0.005(2011):545. |
入库方式： OAI收割
来源：上海药物研究所
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