Biological Activity of Endophytic Fungi from the Roots of the Medicinal Plant Vernonia anthelmintica
文献类型:期刊论文
作者 | Rustamova, N (Rustamova, Nigora)[ 1,2 ]; Gao, YH (Gao, Yanhua)[ 1 ]; Zhang, Y (Zhang, Yong)[ 3 ]; Yili, A (Yili, Abulimiti)[ 1 ] |
刊名 | MICROORGANISMS |
出版日期 | 2020 |
卷号 | 8期号:4页码:1-15 |
ISSN号 | 2076-2607 |
关键词 | endophytic microorganisms Vernonia anthelmintica Aspergillus genus GC MS analysis cytotoxic activity antimicrobial activity |
DOI | 10.3390/microorganisms8040586 |
英文摘要 | Endophytic fungi were first isolated from the fresh root of the Chinese medicinal plant Vernonia anthelmintica collected from the Hotan Prefecture within the Xinjiang Autonomous region of the People's Republic of China. This plant has been used in Uyghur traditional medicine to treat vitiligo, a skin condition characterized by patches of the skin losing their pigment. In total, fifteen fungal strains were isolated. Among these, four endophytic fungi were identified by their DNA sequences and registered to GenBank with accession numbers. The isolates were identified as Schizophyllum commune XJA1, Talaromyces sp. XJA4, Aspergillus sp. XJA6, Aspergillus terreus XJA8. Ethyl acetate extracts of all fungal strains were used to quantify melanin content and to identify in vitro biological activity assays including antimicrobial, antioxidant, cytotoxic, antidiabetic and tyrosinase activity on B16 cells. Among the extracts of all four identified strains, the ethyl acetate extract of the Aspergillus sp. XJA6 was chosen for further characterization because it presented the highest biological activity against these tests. In addition, twenty four volatile compounds from the petroleum ether fraction were characterized by GC-MS. |
WOS记录号 | WOS:000533510400150 |
源URL | [http://ir.xjipc.cas.cn/handle/365002/7679] |
专题 | 新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室 新疆理化技术研究所_资源化学研究室 |
通讯作者 | Yili, A (Yili, Abulimiti)[ 1 ] |
作者单位 | 1.Shanghai Jiao Tong Univ, Sch Life Sci & Biotechnol, State Key Lab Microbial Metab, 800 Dongchuan Rd, Shanghai 200240, Peoples R China 2.Univ Chinese Acad Sci, 19 A Yuquan Rd, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Reg, Urumqi 830011, Peoples R China |
推荐引用方式 GB/T 7714 | Rustamova, N ,Gao, YH ,Zhang, Y ,et al. Biological Activity of Endophytic Fungi from the Roots of the Medicinal Plant Vernonia anthelmintica[J]. MICROORGANISMS,2020,8(4):1-15. |
APA | Rustamova, N ,Gao, YH ,Zhang, Y ,&Yili, A .(2020).Biological Activity of Endophytic Fungi from the Roots of the Medicinal Plant Vernonia anthelmintica.MICROORGANISMS,8(4),1-15. |
MLA | Rustamova, N ,et al."Biological Activity of Endophytic Fungi from the Roots of the Medicinal Plant Vernonia anthelmintica".MICROORGANISMS 8.4(2020):1-15. |
入库方式: OAI收割
来源:新疆理化技术研究所
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