Advances in the Research of Bioinks Based on Natural Collagen, Polysaccharide and Their Derivatives for Skin 3D Bioprinting
文献类型:期刊论文
作者 | Xu, Jie4; Zheng, Shuangshuang3; Hu, Xueyan4; Li, Liying4; Li, Wenfang4; Parungao, Roxanne2; Wang, Yiwei2; Nie, Yi1,3; Liu, Tianqing4; Song, Kedong4 |
刊名 | POLYMERS |
出版日期 | 2020-06-01 |
卷号 | 12期号:6页码:31 |
关键词 | Bioink Skin Tissue Engineering 3d Bioprinting Wound Healing Skin Regeneration |
DOI | 10.3390/polym12061237 |
英文摘要 | The skin plays an important role in protecting the human body, and wound healing must be set in motion immediately following injury or trauma to restore the normal structure and function of skin. The extracellular matrix component of the skin mainly consists of collagen, glycosaminoglycan (GAG), elastin and hyaluronic acid (HA). Recently, natural collagen, polysaccharide and their derivatives such as collagen, gelatin, alginate, chitosan and pectin have been selected as the matrix materials of bioink to construct a functional artificial skin due to their biocompatible and biodegradable properties by 3D bioprinting, which is a revolutionary technology with the potential to transform both research and medical therapeutics. In this review, we outline the current skin bioprinting technologies and the bioink components for skin bioprinting. We also summarize the bioink products practiced in research recently and current challenges to guide future research to develop in a promising direction. While there are challenges regarding currently available skin bioprinting, addressing these issues will facilitate the rapid advancement of 3D skin bioprinting and its ability to mimic the native anatomy and physiology of skin and surrounding tissues in the future. |
WOS关键词 | Extracellular-matrix Bioink ; Growth-factor ; Stem-cells ; Biofabrication Strategies ; Macrophage Recruitment ; Tissue Constructs ; Pectin Hydrogels ; Hyaluronic-acid ; Drug-delivery ; Scaffolds |
资助项目 | National Natural Science Foundation of China[31670978/31370991/21676041] ; Fok Ying Tung Education Foundation[132027] ; State Key Laboratory of Fine Chemicals[KF1111] ; Natural Science Foundation of Liaoning[20180510028] |
WOS研究方向 | Polymer Science |
语种 | 英语 |
出版者 | MDPI |
WOS记录号 | WOS:000553522300001 |
资助机构 | National Natural Science Foundation of China ; Fok Ying Tung Education Foundation ; State Key Laboratory of Fine Chemicals ; Natural Science Foundation of Liaoning |
源URL | [http://ir.ipe.ac.cn/handle/122111/41563] |
专题 | 中国科学院过程工程研究所 |
通讯作者 | Nie, Yi; Liu, Tianqing; Song, Kedong |
作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Key Lab Green Proc & Engn, Beijing 100190, Peoples R China 2.Univ Sydney, ANZAC Res Inst, Burns Res Grp, Concord, NSW 2139, Australia 3.Zhengzhou Inst Emerging Ind Technol, Zhengzhou 450000, Peoples R China 4.Dalian Univ Technol, Dalian R&D Ctr Stem Cell & Tissue Engn, State Key Lab Fine Chem, Dalian 116024, Peoples R China |
推荐引用方式 GB/T 7714 | Xu, Jie,Zheng, Shuangshuang,Hu, Xueyan,et al. Advances in the Research of Bioinks Based on Natural Collagen, Polysaccharide and Their Derivatives for Skin 3D Bioprinting[J]. POLYMERS,2020,12(6):31. |
APA | Xu, Jie.,Zheng, Shuangshuang.,Hu, Xueyan.,Li, Liying.,Li, Wenfang.,...&Song, Kedong.(2020).Advances in the Research of Bioinks Based on Natural Collagen, Polysaccharide and Their Derivatives for Skin 3D Bioprinting.POLYMERS,12(6),31. |
MLA | Xu, Jie,et al."Advances in the Research of Bioinks Based on Natural Collagen, Polysaccharide and Their Derivatives for Skin 3D Bioprinting".POLYMERS 12.6(2020):31. |
入库方式: OAI收割
来源:过程工程研究所
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