中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Advances in the Research of Bioinks Based on Natural Collagen, Polysaccharide and Their Derivatives for Skin 3D Bioprinting

文献类型:期刊论文

作者Xu, Jie4; Zheng, Shuangshuang3; Hu, Xueyan4; Li, Liying4; Li, Wenfang4; Parungao, Roxanne2; Wang, Yiwei2; Nie, Yi1,3; Liu, Tianqing4; Song, Kedong4
刊名POLYMERS
出版日期2020-06-01
卷号12期号:6页码:31
关键词Bioink Skin Tissue Engineering 3d Bioprinting Wound Healing Skin Regeneration
DOI10.3390/polym12061237
英文摘要

The skin plays an important role in protecting the human body, and wound healing must be set in motion immediately following injury or trauma to restore the normal structure and function of skin. The extracellular matrix component of the skin mainly consists of collagen, glycosaminoglycan (GAG), elastin and hyaluronic acid (HA). Recently, natural collagen, polysaccharide and their derivatives such as collagen, gelatin, alginate, chitosan and pectin have been selected as the matrix materials of bioink to construct a functional artificial skin due to their biocompatible and biodegradable properties by 3D bioprinting, which is a revolutionary technology with the potential to transform both research and medical therapeutics. In this review, we outline the current skin bioprinting technologies and the bioink components for skin bioprinting. We also summarize the bioink products practiced in research recently and current challenges to guide future research to develop in a promising direction. While there are challenges regarding currently available skin bioprinting, addressing these issues will facilitate the rapid advancement of 3D skin bioprinting and its ability to mimic the native anatomy and physiology of skin and surrounding tissues in the future.

WOS关键词Extracellular-matrix Bioink ; Growth-factor ; Stem-cells ; Biofabrication Strategies ; Macrophage Recruitment ; Tissue Constructs ; Pectin Hydrogels ; Hyaluronic-acid ; Drug-delivery ; Scaffolds
资助项目National Natural Science Foundation of China[31670978/31370991/21676041] ; Fok Ying Tung Education Foundation[132027] ; State Key Laboratory of Fine Chemicals[KF1111] ; Natural Science Foundation of Liaoning[20180510028]
WOS研究方向Polymer Science
语种英语
出版者MDPI
WOS记录号WOS:000553522300001
资助机构National Natural Science Foundation of China ; Fok Ying Tung Education Foundation ; State Key Laboratory of Fine Chemicals ; Natural Science Foundation of Liaoning
源URL[http://ir.ipe.ac.cn/handle/122111/41563]  
专题中国科学院过程工程研究所
通讯作者Nie, Yi; Liu, Tianqing; Song, Kedong
作者单位1.Chinese Acad Sci, Inst Proc Engn, Key Lab Green Proc & Engn, Beijing 100190, Peoples R China
2.Univ Sydney, ANZAC Res Inst, Burns Res Grp, Concord, NSW 2139, Australia
3.Zhengzhou Inst Emerging Ind Technol, Zhengzhou 450000, Peoples R China
4.Dalian Univ Technol, Dalian R&D Ctr Stem Cell & Tissue Engn, State Key Lab Fine Chem, Dalian 116024, Peoples R China
推荐引用方式
GB/T 7714
Xu, Jie,Zheng, Shuangshuang,Hu, Xueyan,et al. Advances in the Research of Bioinks Based on Natural Collagen, Polysaccharide and Their Derivatives for Skin 3D Bioprinting[J]. POLYMERS,2020,12(6):31.
APA Xu, Jie.,Zheng, Shuangshuang.,Hu, Xueyan.,Li, Liying.,Li, Wenfang.,...&Song, Kedong.(2020).Advances in the Research of Bioinks Based on Natural Collagen, Polysaccharide and Their Derivatives for Skin 3D Bioprinting.POLYMERS,12(6),31.
MLA Xu, Jie,et al."Advances in the Research of Bioinks Based on Natural Collagen, Polysaccharide and Their Derivatives for Skin 3D Bioprinting".POLYMERS 12.6(2020):31.

入库方式: OAI收割

来源:过程工程研究所

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