Antibiotic resistance gene profiling in response to antibiotic usage and environmental factors in the surface water and groundwater of Honghu Lake, China
文献类型：期刊论文
| 作者 | Tong, Lei2; Qin, Liting2; Guan, Chuan2; Wilson, Mesmire Emade2; Li, Xianju1; Cheng, Dandan2; Ma, Jie2; Liu, Hui2; Gong, Fujun3 |
| 刊名 | ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
 |
| 出版日期 | 2020-06-06 |
| 页码 | 11 |
| 关键词 | Antibiotic Acetylated metabolite Antibiotic resistance gene Groundwater Aquaculture Honghu Lake |
| ISSN号 | 0944-1344 |
| DOI | 10.1007/s11356-020-09487-5 |
| 英文摘要 | There is an increasing concern that aquaculture has been implicated in the formation of antibiotic resistance gene (ARG) reservoirs; however, little is known about the consequences of their presence in groundwater. In this study, 22 antibiotics, including four acetylated metabolites, and 27 ARGs were analyzed in fish pond water, surface water, and groundwater of the Honghu Lake in China. Correlations between conventional parameters, ionic composition, antibiotic concentration, and relative abundance of ARGs in water samples were analyzed. Among the three different sources of water, total antibiotic levels were the highest in fish pond water and the lowest in groundwater, with moderate levels in lake water. In surface water, sulfonamides and their metabolites accounted for the highest antibiotic content, whereas tetracyclines were the most frequently found in groundwater samples. Despite the near-undetectable levels of antibiotics in groundwater, the relative abundance of ARGs in groundwater samples was even higher than that in surface waters. The magnitude and extent of ARG migration are likely to be dependent on local antibiotic contamination levels as well as on the local environmental and hydrogeological conditions, with the class 1 integrons (intI1) being essential for the dissemination of such ARGs. The effects of environmental parameters such as antibiotics, dissolved oxygen, HCO3-, and pH on ARGs were highly significant, reflecting the potential impact of these factors on the abundance of ARGs. Our findings thus highlight the need for improved control of the spread of ARGs in and from aquaculture environments. |
| 资助项目 | National Natural Science Foundation of China[41772364] ; National Natural Science Foundation of China[41521001] ; Fundamental Research Funds for the Central Universities, China University of Geosciences (Wuhan)[CUG170103] ; Fundamental Research Funds for the Central Universities, China University of Geosciences (Wuhan)[CUGCJ1702] |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:000538359100007 |
| 出版者 | SPRINGER HEIDELBERG |
| 源URL | [http://202.127.146.157/handle/2RYDP1HH/15343]  |
| 专题 | 中国科学院武汉植物园 |
| 通讯作者 | Tong, Lei |
| 作者单位 | 1.China Univ Geosci, Sch Comp Sci, Wuhan 430074, Peoples R China 2.China Univ Geosci, Sch Environm Studies, Wuhan 430074, Peoples R China 3.Chinese Acad Sci, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan Bot Garden, Wuhan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tong, Lei,Qin, Liting,Guan, Chuan,et al. Antibiotic resistance gene profiling in response to antibiotic usage and environmental factors in the surface water and groundwater of Honghu Lake, China[J]. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,2020:11. |
| APA | Tong, Lei.,Qin, Liting.,Guan, Chuan.,Wilson, Mesmire Emade.,Li, Xianju.,...&Gong, Fujun.(2020).Antibiotic resistance gene profiling in response to antibiotic usage and environmental factors in the surface water and groundwater of Honghu Lake, China.ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,11. |
| MLA | Tong, Lei,et al."Antibiotic resistance gene profiling in response to antibiotic usage and environmental factors in the surface water and groundwater of Honghu Lake, China".ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020):11. |
入库方式： OAI收割
来源：武汉植物园
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