Metagenome sequencing to unveil the resistome in a deep subtropical lake on the Yunnan-Guizhou Plateau, China
文献类型：期刊论文
| 作者 | Pan, Xiong2; Lin, Li2; Zhang, Weihong1,3; Dong, Lei2; Yang, Yuyi1,3 |
| 刊名 | ENVIRONMENTAL POLLUTION
 |
| 出版日期 | 2020-08-01 |
| 卷号 | 263页码:8 |
| 关键词 | Metagenomic analysis Bacterial community Resistance genes Spatial analysis Erhai lake |
| ISSN号 | 0269-7491 |
| DOI | 10.1016/j.envpol.2020.114470 |
| 英文摘要 | Erhai Lake in the Yunnan-Guizhou Plateau, a typical subtropical deep lake, experienced long-time input of nutrients and pollutants, which provides beneficial conditions for evolution and spread of resistance genes. In this study, the profile of bacterial community, antibiotic and metal resistance genes in sediments of Erhai Lake were analyzed via high-thought sequencing of 16S rRNA and metagenomic DNA. Proteobacteria, Firmicutes, Nitrospirae, and Bacteroidetes were found to be the main composition of the bacterial community. Multidrug-, bacitracin-, macrolide-lincosamide-streptogramin (MLS)- and tetracycline resistance genes were the primary antibiotic resistance gene (ARG) types with high relative abundance, whereas Multi-metal-, and arsenic- resistance genes were the primary metal resistance gene (MRG) types. The effects of nitrogen and phosphorus on the abundance of ARGs and MRGs depended on the different types. Some specific ARG (fosmidomycin resistance genes) and MRG types (multi-metal resistance genes) also showed significant geographic distribution. Bacterial community was the main driver shaping the resistome. Nutrients also played an essential role in structuring the bacterial community and resistome in the sediments of Erhai Lake. This study sheds light on the distribution and fate of resistome under a high load of nitrogen and phosphorus in a deep lake. (C) 2020 Elsevier Ltd. All rights reserved. |
| 资助项目 | Fundamental Research Funds for Central Public Welfare Research Institutes of China[CKSF2019380SH] ; Fundamental Research Funds for Central Public Welfare Research Institutes of China[CKSF2017062/SH] ; Chinese Academy of Sciences Strategic Pilot Science and Technology Project[XDA23040000] |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:000539427600082 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://202.127.146.157/handle/2RYDP1HH/15415]  |
| 专题 | 中国科学院武汉植物园 |
| 通讯作者 | Yang, Yuyi |
| 作者单位 | 1.Chinese Acad Sci, Ctr Plant Ecol, Core Bot Gardens, Wuhan 430074, Peoples R China 2.Changjiang River Sci Res Inst, Basin Water Environm Res Dept, Wuhan 430014, Peoples R China 3.Chinese Acad Sci, Key Lab Aquat Bot & Watershed Ecol, Wuhan Bot Garden, Wuhan 430074, Peoples R China |
| 推荐引用方式 GB/T 7714 | Pan, Xiong,Lin, Li,Zhang, Weihong,et al. Metagenome sequencing to unveil the resistome in a deep subtropical lake on the Yunnan-Guizhou Plateau, China[J]. ENVIRONMENTAL POLLUTION,2020,263:8. |
| APA | Pan, Xiong,Lin, Li,Zhang, Weihong,Dong, Lei,&Yang, Yuyi.(2020).Metagenome sequencing to unveil the resistome in a deep subtropical lake on the Yunnan-Guizhou Plateau, China.ENVIRONMENTAL POLLUTION,263,8. |
| MLA | Pan, Xiong,et al."Metagenome sequencing to unveil the resistome in a deep subtropical lake on the Yunnan-Guizhou Plateau, China".ENVIRONMENTAL POLLUTION 263(2020):8. |
入库方式： OAI收割
来源：武汉植物园
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