Regeneration-Related Functional Cargoes in Mesenchymal Stem Cell-Derived Small Extracellular Vesicles
文献类型：期刊论文
| 作者 | Zhu, Zhongyi4,5; Zhang, Yijing4,5; Hua, Keqin4,5; Ding, Jingxin4,5; Zhang, Yijing3; Wu, Ligang1,2; , |
| 刊名 | STEM CELLS AND DEVELOPMENT
 |
| 出版日期 | 2020 |
| 卷号 | 29期号:1页码:15-24 |
| ISSN号 | 1547-3287 |
| 关键词 | STROMAL CELLS IN-VITRO EXOSOMES MICRORNAS INJURY DIFFERENTIATION ENHANCE REPAIR MODULATION CISPLATIN |
| DOI | 10.1089/scd.2019.0131 |
| 文献子类 | Article |
| 英文摘要 | Mesenchymal stem cell-derived small extracellular vesicles (MSC-sEV) are the primary effective source in stem cell-dependent regenerative medicine due to their preponderances over direct MSC implantation. An increasing number of studies have been carried out on MSC-sEV derived from different types of cells, and their function of accelerating tissue repair was proved. However, only a few researches were able to demonstrate the functional cargoes in MSC-sEV or their mechanisms in promoting tissue recovery. In this review, we present current achievements in discovering MSC-sEV-carried RNAs and proteins as promoters in tissue regeneration. Their therapeutic function includes modulating immune reactivity, promoting angiogenesis, and accelerating cell proliferation and migration through orchestrates of cell signaling pathways. |
| 学科主题 | Cell & Tissue Engineering ; Hematology ; Medicine, Research & Experimental ; Transplantation |
| WOS关键词 | stem cell ; regeneration ; small extracellular vesicle ; microRNA ; lncRNA ; protein |
| 语种 | 英语 |
| WOS记录号 | WOS:000505317100002 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/3578]  |
| 专题 | 生化所2019-2020年发文 |
| 作者单位 | 1.Univ Chinese Acad Sci, Shanghai, Peoples R China, 2.Chinese Acad Sci, Shanghai Inst Biochem & Cell Biol, CAS Ctr Excellence Mol Cell Sci, State Key Lab Mol Biol, Shanghai, Peoples R China; 3.Shanghai Ji Ai Genet & IVF Inst, Shanghai, Peoples R China; 4.Shanghai Key Lab Female Reprod Endocrine Related, Shanghai, Peoples R China; 5.Fudan Univ, Obstet & Gynecol Hosp, Dept Gynecol, Shanghai, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Zhu, Zhongyi,Zhang, Yijing,Hua, Keqin,et al. Regeneration-Related Functional Cargoes in Mesenchymal Stem Cell-Derived Small Extracellular Vesicles[J]. STEM CELLS AND DEVELOPMENT,2020,29(1):15-24. |
| APA | Zhu, Zhongyi.,Zhang, Yijing.,Hua, Keqin.,Ding, Jingxin.,Zhang, Yijing.,...&,.(2020).Regeneration-Related Functional Cargoes in Mesenchymal Stem Cell-Derived Small Extracellular Vesicles.STEM CELLS AND DEVELOPMENT,29(1),15-24. |
| MLA | Zhu, Zhongyi,et al."Regeneration-Related Functional Cargoes in Mesenchymal Stem Cell-Derived Small Extracellular Vesicles".STEM CELLS AND DEVELOPMENT 29.1(2020):15-24. |
入库方式： OAI收割
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。