Autophagy in Development and Differentiation
文献类型：期刊论文
| 作者 | Hu, Yang-Xi2; Han, Xiao-Shuai1; Jing, Qing1; , |
| 刊名 | AUTOPHAGY: BIOLOGY AND DISEASES: BASIC SCIENCE
 |
| 出版日期 | 2019 |
| 卷号 | 1206期号:-页码:469-487 |
| 关键词 | Autophagy Development Differentiation Invertebrates Stem cells |
| ISSN号 | 0065-2598 |
| DOI | 10.1007/978-981-15-0602-4_22 |
| 文献子类 | Article; Book Chapter |
| 英文摘要 | Autophagy is crucial in the differentiation and development of both mammals and invertebrates, as a rapid response to environmental and hormonal stimuli. Autophagy is also important for intracellular renewal, maintaining the health of terminally differentiated cells. Studies of Drosophila, Caenorhabditis elegans, and other species revealed abnormal autophagy lead to developmental and differential abnormality, including those in salivary glands and midgut development, protein aggregation, removal of apoptotic cell corpses, and development of dauer and synapse. Autophagy also participates in the development of mammalian embryos before implantation into the uterus, adaption to the nascent hunger environment, blood cells production, and cell differentiation in adipogenesis. Autophagy found in various stem cells, like hematopoietic stem cells, bone marrow mesenchymal stem cells and neural stem cells (NSCs), is tightly associated with their self-renewal, directed differentiation, and senescence. |
| 学科主题 | Immunology |
| WOS关键词 | PROGRAMMED CELL-DEATH ; STEM-CELLS ; BASAL AUTOPHAGY ; GROWTH ARREST ; PROLIFERATION ; MTOR ; DEGRADATION ; APOPTOSIS ; BECLIN-1 ; RENEWAL |
| 语种 | 英语 |
| CSCD记录号 | CSCD:31776999 |
| WOS记录号 | WOS:000514094300022 |
| 出版者 | SPRINGER-VERLAG SINGAPORE PTE LTD |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/664]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所 |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Nutr & Hlth, CAS Key Lab Tissue Microenvironm & Tumor, 320 Yueyang Rd, Shanghai 200031, Peoples R China, 2.Shanghai Changhai Hosp, Dept Cardiol, 168 Changhai Rd, Shanghai 200433, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Hu, Yang-Xi,Han, Xiao-Shuai,Jing, Qing,et al. Autophagy in Development and Differentiation[J]. AUTOPHAGY: BIOLOGY AND DISEASES: BASIC SCIENCE,2019,1206(-):469-487. |
| APA | Hu, Yang-Xi,Han, Xiao-Shuai,Jing, Qing,&,.(2019).Autophagy in Development and Differentiation.AUTOPHAGY: BIOLOGY AND DISEASES: BASIC SCIENCE,1206(-),469-487. |
| MLA | Hu, Yang-Xi,et al."Autophagy in Development and Differentiation".AUTOPHAGY: BIOLOGY AND DISEASES: BASIC SCIENCE 1206.-(2019):469-487. |
入库方式： OAI收割
来源：上海营养与健康研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。