The associations between plasma phytoestrogens concentration and metabolic syndrome risks in Chinese population
文献类型:期刊论文
作者 | Liu, Jie2; Li, Xiang2; Jia, Keyu2; Zhao, Jing2; Zhang, Hong1,2; Gao, Ying2; Mi, Shengquan3; Du, Li1; Zhao, Wenhua4; , |
刊名 | PLOS ONE
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出版日期 | 2018 |
卷号 | 13期号:3页码:e0194639 |
关键词 | catalase-like activity iron oxide nanoparticles autophagy cytotoxicity reactive oxygen species |
ISSN号 | 1932-6203 |
DOI | 10.1371/journal.pone.0194639 |
文献子类 | Article |
英文摘要 | Metabolic syndrome (MetS) has become an important issue in the healthcare systems of both developed and developing countries. Phytoestrogens have shown estrogenic effects, which may involve in the etiology of MetS. The current study consisted of 293 MetS cases and 264 healthy controls. The concentrations of seven plasma phytoestrogens (daidzein, genistein, glycitein, equol, enterolactone, enterodiol and coumestrol) were detected by UPLC-MS/MS. Adjusted unconditional logistic regression was used to assess the associations between plasma phytoestrogens concentration and risks of MetS, as well as the associations between plasma phytoestrogens concentration and MetS components. Linear regression was used to evaluate the associations between equol concentration in equol-producers and MetS components. Higher concentrations of total isoflavone and equol were associated with decreased risk of MetS. The equol concentration was negatively associated with waist circumference and positively associated with HDL-C level. Increased daidzein was associated with both lower waist circumference and lower fasting blood glucose levels. Our results suggested that higher plasma total isoflavone, equol and daidzein might decrease MetS risk. |
学科主题 | Science & Technology - Other Topics |
WOS关键词 | HUMAN ESTROGEN-RECEPTOR ; SOY FOOD-INTAKE ; POSTMENOPAUSAL WOMEN ; BLOOD-PRESSURE ; DIETARY PHYTOESTROGENS ; PROSTATE-CANCER ; EQUOL PRODUCERS ; WEIGHT-LOSS ; ISOFLAVONES ; SERUM |
语种 | 英语 |
WOS记录号 | WOS:000427901500047 |
出版者 | PUBLIC LIBRARY SCIENCE |
版本 | 出版稿 |
源URL | [http://202.127.25.144/handle/331004/737] ![]() |
专题 | 中国科学院上海生命科学研究院营养科学研究所 |
作者单位 | 1.Fudan Univ, Inst Biostat, Sch Life Sci, Shanghai, Peoples R China; 2.Univ Chinese Acad Sci, Chinese Acad Sci, Shanghai Inst Biol Sci, Key Lab Nutr & Metab,Inst Nutr Sci, Shanghai, Peoples R China; 3.Beijing Union Univ, Coll Biochem Engn, Beijing, Peoples R China; 4.Chinese Ctr Dis Control & Prevent, Natl Inst Nutr & Hlth, Beijing, Peoples R China, |
推荐引用方式 GB/T 7714 | Liu, Jie,Li, Xiang,Jia, Keyu,et al. The associations between plasma phytoestrogens concentration and metabolic syndrome risks in Chinese population[J]. PLOS ONE,2018,13(3):e0194639. |
APA | Liu, Jie.,Li, Xiang.,Jia, Keyu.,Zhao, Jing.,Zhang, Hong.,...&,.(2018).The associations between plasma phytoestrogens concentration and metabolic syndrome risks in Chinese population.PLOS ONE,13(3),e0194639. |
MLA | Liu, Jie,et al."The associations between plasma phytoestrogens concentration and metabolic syndrome risks in Chinese population".PLOS ONE 13.3(2018):e0194639. |
入库方式: OAI收割
来源:上海营养与健康研究所
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