Genetic structure of Tibetan populations in Gansu revealed by forensic STR loci
文献类型：期刊论文
| 作者 | Yao, Hong-Bing3; Tao, Xiaolan3; Ma, Liying3; Wang, Chuan-Chao4,5,6,7; Wen, Shao-Qing4; Jin, Li4,5; Li, Hui4,5; Krause, Johannes6,7; Wang, Jiang8; Shang, Lei9 |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:-页码:41195 |
| 关键词 | gene expression intracranial EEG memory neocortex |
| ISSN号 | 2045-2322 |
| DOI | 10.1038/srep41195 |
| 文献子类 | Article |
| 英文摘要 | The origin and diversification of Sino-Tibetan speaking populations have been long-standing hot debates. However, the limited genetic information of Tibetan populations keeps this topic far from clear. In the present study, we genotyped 15 forensic autosomal short tandem repeats (STRs) from 803 unrelated Tibetan individuals from Gansu Province (635 from Gannan and 168 from Tianzhu) in northwest China. We combined these data with published dataset to infer a detailed population affinities and genetic substructure of Sino-Tibetan populations. Our results revealed Tibetan populations in Gannan and Tianzhu are genetically very similar with Tibetans from other regions. The Tibetans in Tianzhu have received more genetic influence from surrounding lowland populations. The genetic structure of Sino-Tibetan populations was strongly correlated with linguistic affiliations. Although the among-population variances are relatively small, the genetic components for Tibetan, Lolo-Burmese, and Han Chinese were quite distinctive, especially for the Deng, Nu, and Derung of Lolo-Burmese. Han Chinese but not Tibetans are suggested to share substantial genetic component with southern natives, such as Tai-Kadai and Hmong-Mien speaking populations, and with other lowland East Asian populations, which implies there might be extensive gene flow between those lowland groups and Han Chinese after Han Chinese were separated from Tibetans. The dataset generated in present study is also valuable for forensic identification and paternity tests in China. |
| 学科主题 | Science & Technology - Other Topics |
| WOS关键词 | TANDEM REPEATS STRS ; EAST-ASIAN ORIGIN ; ALLELE FREQUENCIES ; NEOLITHIC EXPANSION ; HAN POPULATION ; MAINLAND CHINA ; HIGH-ALTITUDE ; REGION ; HIMALAYAS ; PLATEAU |
| 语种 | 英语 |
| WOS记录号 | WOS:000392420100001 |
| 出版者 | NATURE PUBLISHING GROUP |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/769]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所 |
| 作者单位 | 1.Peoples Hosp Zhengzhou Univ, Henan Prov Peoples Hosp, Inst Med Genet, Zhengzhou, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Biol Sci, CAS MPG Partner Inst Computat Biol, Shanghai 200031, Peoples R China, 3.Gansu Inst Polit Sci & Law, Key Lab Evidence Sci Gansu Prov, Lanzhou 730070, Peoples R China; 4.Fudan Univ, Sch Life Sci, Collaborat Innovat Ctr Genet & Dev, State Key Lab Genet Engn, Shanghai 200433, Peoples R China; 5.Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Sch Life Sci, Key Lab Contemporary Anthropol,Minist Educ, Shanghai 200433, Peoples R China; 6.Max Planck Inst Sci Human Hist, Dept Archaeogenet, Kahlaische Str 10, D-07745 Jena, Germany; 7.Max Planck Inst Sci Human Hist, Eurasia3angle Res Grp, Kahlaische Str 10, D-07745 Jena, Germany; 8.Henan Agr Univ, Coll Anim Sci & Vet Med, Zhengzhou 450002, Henan Province, Peoples R China; 9.Minist Publ Secur, Inst Forens Sci, Key Lab Forens Genet, Beijing 100038, Peoples R China; 10.Lanzhou Univ, Hosp Clin Lab 2, Lanzhou 730000, Gansu, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Yao, Hong-Bing,Tao, Xiaolan,Ma, Liying,et al. Genetic structure of Tibetan populations in Gansu revealed by forensic STR loci[J]. SCIENTIFIC REPORTS,2017,7(-):41195. |
| APA | Yao, Hong-Bing.,Tao, Xiaolan.,Ma, Liying.,Wang, Chuan-Chao.,Wen, Shao-Qing.,...&,.(2017).Genetic structure of Tibetan populations in Gansu revealed by forensic STR loci.SCIENTIFIC REPORTS,7(-),41195. |
| MLA | Yao, Hong-Bing,et al."Genetic structure of Tibetan populations in Gansu revealed by forensic STR loci".SCIENTIFIC REPORTS 7.-(2017):41195. |
入库方式： OAI收割
来源：上海营养与健康研究所
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