Chemical proteomics reveal CD147 as a functional target of pseudolaric acid B in human cancer cells
文献类型：期刊论文
| 作者 | Zhou, Yiqing1; Di, Zhengao1; Li, Weichao1; Xiao, Youli1,3,4; Li, Xiaoming2,3; Zhang, Haibing2; Shan, Yuanhong4; , |
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2017 |
| 卷号 | 53期号:62页码:8671-8674 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c7cc04345g |
| 文献子类 | Article |
| 英文摘要 | CD147 is a glycosylated transmembrane protein highly expressed on the surface of various tumor cells which plays vital roles in tumor invasion, progression and metastasis. We report the discovery of the natural product pseudolaric acid B (PAB) directly targeting CD147 by chemical proteomics utilizing a PAB-derived photoaffinity probe which could serve as a novel type of anticancer reagent. |
| 学科主题 | Chemistry |
| WOS关键词 | INHIBITS ANGIOGENESIS ; CELLULAR TARGETS ; AGENT ; HAB18G/CD147 ; APOPTOSIS ; TUBULIN ; PATHWAY ; BINDING ; KINASE ; ERK1/2 |
| 语种 | 英语 |
| WOS记录号 | WOS:000406669000009 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/795]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所 |
| 作者单位 | 1.Chinese Acad Sci, Ctr Excellence Mol Plant Sci, Shanghai Inst Biol Sci, Inst Plant Physiol & Ecol,Key Lab Synthetic Biol, Shanghai 200032, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci, Shanghai 200032, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China; 4.Chinese Acad Sci, Core Facil Ctr Inst Plant Physiol & Ecol, Shanghai Inst Biol Sci, Shanghai 200032, Peoples R China, |
| 推荐引用方式 GB/T 7714 | Zhou, Yiqing,Di, Zhengao,Li, Weichao,et al. Chemical proteomics reveal CD147 as a functional target of pseudolaric acid B in human cancer cells[J]. CHEMICAL COMMUNICATIONS,2017,53(62):8671-8674. |
| APA | Zhou, Yiqing.,Di, Zhengao.,Li, Weichao.,Xiao, Youli.,Li, Xiaoming.,...&,.(2017).Chemical proteomics reveal CD147 as a functional target of pseudolaric acid B in human cancer cells.CHEMICAL COMMUNICATIONS,53(62),8671-8674. |
| MLA | Zhou, Yiqing,et al."Chemical proteomics reveal CD147 as a functional target of pseudolaric acid B in human cancer cells".CHEMICAL COMMUNICATIONS 53.62(2017):8671-8674. |
入库方式： OAI收割
来源：上海营养与健康研究所
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