Adaptation of human skin color in various populations
文献类型：期刊论文
| 作者 | Deng, Lian2,3; Xu, Shuhua2,3; Xu, Shuhua1,4; , |
| 刊名 | HEREDITAS
 |
| 出版日期 | 2017 |
| 卷号 | 155期号:-页码:1 |
| 关键词 | Skin color Natural selection Genetic adaptation Modern humans Archaic hominin |
| ISSN号 | 1601-5223 |
| DOI | 10.1186/s41065-017-0036-2 |
| 文献子类 | Review |
| 英文摘要 | Background: Skin color is a well-recognized adaptive trait and has been studied extensively in humans. Understanding the genetic basis of adaptation of skin color in various populations has many implications in human evolution and medicine. Discussion: Impressive progress has been made recently to identify genes associated with skin color variation in a wide range of geographical and temporal populations. In this review, we discuss what is currently known about the genetics of skin color variation. We enumerated several cases of skin color adaptation in global modern humans and archaic hominins, and illustrated why, when, and how skin color adaptation occurred in different populations. Finally, we provided a summary of the candidate loci associated with pigmentation, which could be a valuable reference for further evolutionary and medical studies. Conclusion: Previous studies generally indicated a complex genetic mechanism underlying the skin color variation, expanding our understanding of the role of population demographic history and natural selection in shaping genetic and phenotypic diversity in humans. Future work is needed to dissect the genetic architecture of skin color adaptation in numerous ethnic minority groups around the world, which remains relatively obscure compared with that of major continental groups, and to unravel the exact genetic basis of skin color adaptation. |
| 学科主题 | Genetics & Heredity |
| WOS关键词 | NORTHERN ISLAND MELANESIA ; RECENT POSITIVE SELECTION ; GENOME-WIDE ASSOCIATION ; RECENT HUMAN-EVOLUTION ; HUMAN PIGMENTATION ; COAT COLOR ; MELANOMA SUSCEPTIBILITY ; PURIFYING SELECTION ; ADAPTIVE EVOLUTION ; NATURAL-SELECTION |
| 语种 | 英语 |
| WOS记录号 | WOS:000405103500001 |
| 出版者 | BIOMED CENTRAL LTD |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/871]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所 |
| 作者单位 | 1.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China; 2.Chinese Acad Sci, Max Planck Independent Res Grp Populat Genom, Key Lab Computat Biol,Shanghai Inst Biol Sci, CAS MPG Partner Inst Computat Biol PICB, Shanghai 200031, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 4.Collaborat Innovat Ctr Genet & Dev, Shanghai 200438, Peoples R China, |
| 推荐引用方式 GB/T 7714 | Deng, Lian,Xu, Shuhua,Xu, Shuhua,et al. Adaptation of human skin color in various populations[J]. HEREDITAS,2017,155(-):1. |
| APA | Deng, Lian,Xu, Shuhua,Xu, Shuhua,&,.(2017).Adaptation of human skin color in various populations.HEREDITAS,155(-),1. |
| MLA | Deng, Lian,et al."Adaptation of human skin color in various populations".HEREDITAS 155.-(2017):1. |
入库方式： OAI收割
来源：上海营养与健康研究所
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