CIRCpedia v2: An Updated Database for Comprehensive Circular RNA Annotation and Expression Comparison
文献类型：期刊论文
| 作者 | Dong, Rui1; Ma, Xu-Kai1; Li, Guo-Wei1; Yang, Li1; Yang, Li2; , |
| 刊名 | GENOMICS PROTEOMICS & BIOINFORMATICS
 |
| 出版日期 | 2018 |
| 卷号 | 16期号:4页码:226-233 |
| 关键词 | Circular RNA CircRNA Back-splicing Database CIRCpedia |
| ISSN号 | 1672-0229 |
| DOI | 10.1016/j.gpb.2018.08.001 |
| 文献子类 | Article; Data Paper |
| 英文摘要 | Circular RNAs (circRNAs)from back-splicing of exon(s) have been recently identified to be broadly expressed in eukaryotes, in tissue- and species-specific manners. Although functions of most circRNAs remain elusive, some circRNAs are shown to be functional in gene expression regulation and potentially relate to diseases. Due to their stability, circRNAs can also be used as biomarkers for diagnosis. Profiling circRNAs by integrating their expression among different samples thus provides molecular basis for further functional study of circRNAs and their potential application in clinic. Here, we report CIRCpedia v2, an updated database for comprehensive circRNA annotation from over 180 RNA-seq datasets across six different species. This atlas allows users to search, browse, and download circRNAs with expression features in various cell types/tissues, including disease samples. In addition, the updated database incorporates conservation analysis of circRNAs between humans and mice. Finally, the web interface also contains computational tools to compare circRNA expression among samples. CIRCpedia v2 is accessible at http://www.picb.ac.cn/rnomics/circpedia. |
| 学科主题 | Genetics & Heredity |
| WOS关键词 | EXON CIRCULARIZATION ; CIRCRNA BIOGENESIS ; ABUNDANT ; REVEALS ; GENES |
| 语种 | 英语 |
| WOS记录号 | WOS:000448335600002 |
| 出版者 | ELSEVIER SCIENCE BV |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/874]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所 |
| 作者单位 | 1.Univ Chinese Acad Sci, Shanghai Inst Nutr & Hlth,Shanghai Inst Biol Sci, Chinese Acad Sci,CAS MPG Partner Inst Computat Bi, CAS MPG Partner Inst Computat Biol,CAS Key Lab Co, Shanghai 200031, Peoples R China; 2.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China, |
| 推荐引用方式 GB/T 7714 | Dong, Rui,Ma, Xu-Kai,Li, Guo-Wei,et al. CIRCpedia v2: An Updated Database for Comprehensive Circular RNA Annotation and Expression Comparison[J]. GENOMICS PROTEOMICS & BIOINFORMATICS,2018,16(4):226-233. |
| APA | Dong, Rui,Ma, Xu-Kai,Li, Guo-Wei,Yang, Li,Yang, Li,&,.(2018).CIRCpedia v2: An Updated Database for Comprehensive Circular RNA Annotation and Expression Comparison.GENOMICS PROTEOMICS & BIOINFORMATICS,16(4),226-233. |
| MLA | Dong, Rui,et al."CIRCpedia v2: An Updated Database for Comprehensive Circular RNA Annotation and Expression Comparison".GENOMICS PROTEOMICS & BIOINFORMATICS 16.4(2018):226-233. |
入库方式： OAI收割
来源：上海营养与健康研究所
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