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ChAMP: updated methylation analysis pipeline for Illumina BeadChips

文献类型：期刊论文

作者Tian, Yuan4,5; Yang, Zhen5; Teschendorff, Andrew E.5; Webster, Amy P.4; Beck, Stephan4; Feber, Andrew4; Morris, Tiffany J.1; Teschendorff, Andrew E.2,3; ,
刊名BIOINFORMATICS
出版日期2017
卷号33期号:24页码:3982-3984
关键词Sodium dichloroacetic acid (DCA) SIRT2 warburg effect PDHA1 drug synergy
ISSN号1367-4803
DOI10.1093/bioinformatics/btx513
文献子类Article
英文摘要The Illumina Infinium HumanMethylationEPIC BeadChip is the new platform for high-throughput DNA methylation analysis, effectively doubling the coverage compared to the older 450 K array. Here we present a significantly updated and improved version of the Bioconductor package ChAMP, which can be used to analyze EPIC and 450k data. Many enhanced functionalities have been added, including correction for cell-type heterogeneity, network analysis and a series of interactive graphical user interfaces.
学科主题Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Computer Science ; Mathematical & Computational Biology ; Mathematics
WOS关键词DNA METHYLATION ; REGIONS
语种英语
WOS记录号WOS:000417843000015
出版者OXFORD UNIV PRESS
版本出版稿
源URL[http://202.127.25.144/handle/331004/913]  
专题中国科学院上海生命科学研究院营养科学研究所
作者单位1.Cambridge Epigenetix, Jonas Webb Bldg,Babraham Campus, Cambridge CB22 3AT, England;
2.UCL, Dept Womens Canc, London WC1E 6AU, England,
3.UCL, UCL Canc Inst, Stat Genom, London WC1E 6BT, England;
4.UCL, UCL Canc Inst, Med Genom Grp, Paul OGorman Bldg, London WC1E 6BT, England;
5.Univ Chinese Acad Sci, CAS Key Lab Computat Biol, CAS MPG Partner Inst Computat Biol, Shanghai Inst Biol Sci,Chinese Acad Sci, Shanghai 200031, Peoples R China;
推荐引用方式
GB/T 7714		 Tian, Yuan,Yang, Zhen,Teschendorff, Andrew E.,et al. ChAMP: updated methylation analysis pipeline for Illumina BeadChips[J]. BIOINFORMATICS,2017,33(24):3982-3984.
APA Tian, Yuan.,Yang, Zhen.,Teschendorff, Andrew E..,Webster, Amy P..,Beck, Stephan.,...&,.(2017).ChAMP: updated methylation analysis pipeline for Illumina BeadChips.BIOINFORMATICS,33(24),3982-3984.
MLA Tian, Yuan,et al."ChAMP: updated methylation analysis pipeline for Illumina BeadChips".BIOINFORMATICS 33.24(2017):3982-3984.

入库方式： OAI收割

来源：上海营养与健康研究所

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