Diagnostic implication of fibrin degradation products and D-dimer in aortic dissection
文献类型：期刊论文
| 作者 | Dong, Jian2; Duan, Xianli2; Feng, Rui2; Feng, Xiang2; Lu, Qingsheng2; Zhou, Jian2; Bao, Junmin2; Jing, Zaiping2; Zhao, Zhiqing3; Jing, Qing1,4,5,6 |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:-页码:43957 |
| 关键词 | Autophagy high-fat diet lipophagy lysosome MTORC1 NAFLD TFEB |
| ISSN号 | 2045-2322 |
| DOI | 10.1038/srep43957 |
| 文献子类 | Article |
| 英文摘要 | Fibrin degradation products (FDP) and D-dimer have been considered to be involved in many vascular diseases. In this study we aimed to explore the diagnostic implication of FDP and D-dimer in aortic dissection patients. 202 aortic dissection patients were collected as the case group, 150 patients with other cardiovascular diseases, including myocardial infarction (MI, n = 45), pulmonary infarction (n = 51) and abdominal aortic aneurysm (n = 54) were collected as non-dissection group, and 27 healthy people were in the blank control group. The FDP and D-dimer levels were detected with immune nephelometry. Logist regression analysis was performed to evaluate the influence of FDP and D-dimer for the aortic dissection patients. ROC curve was used to determine the diagnostic value of FDP and D-dimer. The FDP and D-dimer levels were significantly higher in aortic dissection patients than in non-dissection patients and the healthy controls. FDP and D-dimer were both the risk factors for patients with aortic dissection. From the ROC analysis, diagnostic value of FDP and D-dimer were not high to distinguish aortic dissection patients from the non-dissection patients. However FDP and D-dimer could be valuable diagnostic marker to differentiate aortic dissection patients and healthy controls with both AUC 0.863. |
| 学科主题 | Science & Technology - Other Topics |
| WOS关键词 | STENT-GRAFT PLACEMENT ; LONG-TERM SURVIVAL ; INTERNATIONAL REGISTRY ; VENOUS THROMBOEMBOLISM ; PULMONARY-EMBOLISM ; MANAGEMENT ; INSIGHTS ; IRAD ; IDENTIFICATION ; BIOMARKERS |
| 语种 | 英语 |
| WOS记录号 | WOS:000395739800002 |
| 出版者 | NATURE PUBLISHING GROUP |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/949]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所 |
| 作者单位 | 1.Shanghai Jiao Tong Univ, Sch Med, Shanghai 200092, Peoples R China, 2.Second Mil Med Univ, Changhai Hosp, Dept Vasc Surg, Shanghai 200433, Peoples R China; 3.Second Mil Med Univ, Changhai Hosp, Dept Surg, Shanghai 200433, Peoples R China; 4.Second Mil Med Univ, Changhai Hosp, Dept Cardiol, Shanghai 200433, Peoples R China; 5.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Hlth Sci, Key Lab Stem Cell Biol, Shanghai 200092, Peoples R China; 6.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Hlth Sci, Lab Nucle Acid & Mol Med, Shanghai 200092, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Dong, Jian,Duan, Xianli,Feng, Rui,et al. Diagnostic implication of fibrin degradation products and D-dimer in aortic dissection[J]. SCIENTIFIC REPORTS,2017,7(-):43957. |
| APA | Dong, Jian.,Duan, Xianli.,Feng, Rui.,Feng, Xiang.,Lu, Qingsheng.,...&,.(2017).Diagnostic implication of fibrin degradation products and D-dimer in aortic dissection.SCIENTIFIC REPORTS,7(-),43957. |
| MLA | Dong, Jian,et al."Diagnostic implication of fibrin degradation products and D-dimer in aortic dissection".SCIENTIFIC REPORTS 7.-(2017):43957. |
入库方式： OAI收割
来源：上海营养与健康研究所
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