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Tracking the dynamic functional connectivity structure of the human brain across the adult lifespan

文献类型：期刊论文

作者Xia, Yunman1,2; Chen, Qunlin1,2; Shi, Liang1,2; Li, MengZe1,2; Chen, Hong1,2; Qiu, Jiang1,2; Gong, Weikang3,4; ,
刊名HUMAN BRAIN MAPPING
出版日期2019
卷号40期号:3页码:717-728
关键词aging dynamic functional network connectivity graph theory Wechsler adult intelligence scale
ISSN号1065-9471
DOI10.1002/hbm.24385
文献子类Article
英文摘要The transition from early adulthood to the elder is marked by functional and structural brain transformations. Many previous studies examined the correlation between the functional connectivity (FC) and aging using resting-state fMRI. Results showed that the changes in FC are linked to aging as well as the cognitive ability changes. However, some researchers proposed that the FC is not static but dynamic changes during the resting-state fMRI scan. In this study, we examined the correlation between the resting-state dynamic functional network connectivity and age using resting scan data of 434 subjects. The results suggested: (a) age is negatively associated with variability of dynamic functional network connectivity state; (b) the dwell time of each age range spends in each state is different; (c) the dynamic graph metrics curve of each age ranges is different and 19-30 age range has the largest average global efficiency and average local efficiency; (d) some dynamic functional network connectivity measures were correlated to the certain cognitive ability. Overall, the results suggested the changes in dynamic functional network connectivity measures may be a characteristic of the aging process and in further investigations may provide a deep understanding of the aging process.
学科主题Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
WOS关键词NETWORK CONNECTIVITY ; FMRI ; CONNECTOMICS ; SEGREGATION ; PERFORMANCE ; COGNITION ; SYSTEMS
语种英语
WOS记录号WOS:000459789600001
出版者WILEY
版本出版稿
源URL[http://202.127.25.144/handle/331004/1013]  
专题中国科学院上海生命科学研究院营养科学研究所
作者单位1.Minist Educ, Key Lab Cognit & Personal, Chongqing, Peoples R China;
2.Southwest Univ, Sch Psychol, Chongqing 400715, Peoples R China;
3.Chinese Acad Sci, Shanghai Inst Biol Sci, CASMPG Partner Inst Computat Biol, Key Lab Computat Biol, Shanghai, Peoples R China;
4.Univ Chinese Acad Sci, Beijing, Peoples R China,
推荐引用方式
GB/T 7714		 Xia, Yunman,Chen, Qunlin,Shi, Liang,et al. Tracking the dynamic functional connectivity structure of the human brain across the adult lifespan[J]. HUMAN BRAIN MAPPING,2019,40(3):717-728.
APA Xia, Yunman.,Chen, Qunlin.,Shi, Liang.,Li, MengZe.,Chen, Hong.,...&,.(2019).Tracking the dynamic functional connectivity structure of the human brain across the adult lifespan.HUMAN BRAIN MAPPING,40(3),717-728.
MLA Xia, Yunman,et al."Tracking the dynamic functional connectivity structure of the human brain across the adult lifespan".HUMAN BRAIN MAPPING 40.3(2019):717-728.

入库方式： OAI收割

来源：上海营养与健康研究所

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