Unique sequence organization and small RNA expression of a "selfish" B chromosome (vol 126, pg 753, 2017)
文献类型：期刊论文
| 作者 | Li, Yue1,2; Chen, Jian1,2; Jing, Xueyuan A.3,4,5; Aldrich, John C.3,4,5; Clifford, C.3,4,5; Ferree, Patrick M.3,4,5; Akbari, Omar S.6,7; , |
| 刊名 | CHROMOSOMA
 |
| 出版日期 | 2017 |
| 卷号 | 126期号:6页码:781-781 |
| 关键词 | gene expression intracranial EEG memory neocortex |
| ISSN号 | 0009-5915 |
| DOI | 10.1007/s00412-017-0642-9 |
| 文献子类 | Correction |
| 英文摘要 | Memory encoding is an essential step for all learning. However, the genetic and molecular mechanisms underlying human memory encoding remain poorly understood, and how this molecular framework permits the emergence of specific patterns of brain oscillations observed during mnemonic processing is unknown. Here, we directly compare intracranial electroencephalography recordings from the neocortex in individuals performing an episodic memory task with human gene expression from the same areas. We identify genes correlated with oscillatory memory effects across 6 frequency bands. These genes are enriched for autism-related genes and have preferential expression in neurons, in particular genes encoding synaptic proteins and ion channels, supporting the idea that the genes regulating voltage gradients are involved in the modulation of oscillatory patterns during successful memory encoding across brain areas. Memory-related genes are distinct from those correlated with other forms of cognitive processing and resting state fMRI. These data are the first to identify correlations between gene expression and active human brain states as well as provide a molecular window into memory encoding oscillations in the human brain. |
| 学科主题 | Biochemistry & Molecular Biology ; Genetics & Heredity |
| 语种 | 英语 |
| WOS记录号 | WOS:000415626700009 |
| 出版者 | SPRINGER |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/1018]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Stem Cell Biol, Inst Hlth Sci, Shanghai Inst Biol Sci, 320 Yue Yang Rd, Shanghai 200031, Peoples R China; 2.Shanghai Jiao Tong Univ, Sch Med, 320 Yue Yang Rd, Shanghai 200031, Peoples R China; 3.Claremont Mckenna Coll, WM Keck Sci Dept, 925 N Mills Ave, Claremont, CA 91711 USA; 4.Pitzer Coll, WM Keck Sci Dept, 925 N Mills Ave, Claremont, CA 91711 USA; 5.Scripps Coll, WM Keck Sci Dept, 925 N Mills Ave, Claremont, CA 91711 USA; 6.Univ Calif Riverside, Dept Entomol, Inst Integrat Genome Biol, Riverside, CA 92521 USA; 7.Univ Calif Riverside, Ctr Dis Vector Res, Inst Integrat Genome Biol, Riverside, CA 92521 USA, |
| 推荐引用方式 GB/T 7714 | Li, Yue,Chen, Jian,Jing, Xueyuan A.,et al. Unique sequence organization and small RNA expression of a "selfish" B chromosome (vol 126, pg 753, 2017)[J]. CHROMOSOMA,2017,126(6):781-781. |
| APA | Li, Yue.,Chen, Jian.,Jing, Xueyuan A..,Aldrich, John C..,Clifford, C..,...&,.(2017).Unique sequence organization and small RNA expression of a "selfish" B chromosome (vol 126, pg 753, 2017).CHROMOSOMA,126(6),781-781. |
| MLA | Li, Yue,et al."Unique sequence organization and small RNA expression of a "selfish" B chromosome (vol 126, pg 753, 2017)".CHROMOSOMA 126.6(2017):781-781. |
入库方式： OAI收割
来源：上海营养与健康研究所
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