Why, so far, have epidemics always eventually petered out? Quasispecies theory suggests a (testable!) answer
文献类型：期刊论文
| 作者 | Dress, Andreas1,2,3; , |
| 刊名 | EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
 |
| 出版日期 | 2018 |
| 卷号 | 47期号:4页码:427-442 |
| 关键词 | Epidemics Pandemics Propagation dynamics of infectious diseases Quasispecies |
| ISSN号 | 0175-7571 |
| DOI | 10.1007/s00249-018-1306-2 |
| 文献子类 | Article |
| 英文摘要 | In this paper, it is argued that the fact that, so far, even the worst and most far-reaching epidemics-from the Plague of Athens in 430 BC and the Plague of Justinian in 541/542 AD to the Hong Kong Flu from 1968/69-always finally petered out can be explained using Manfred Eigen's quasispecies concept: Indeed, as the infectious agents, while duplicating themselves in the infected organisms, mutate all the time, these infected organisms carry along quite a multitude of mutational variants or-in Manfred Eigen's terms-a whole quasispecies of infectious agents implying that, within that quasispecies, those variants that differ from the wild type may actually serve as some kind of vaccination program when infecting some previously uninfected persons. In this context, some data regarding various recent epidemics will also be illustrated, using Daniel Huson's SplitsTree software tool. |
| 学科主题 | Biophysics |
| WOS关键词 | NETWORKS |
| 语种 | 英语 |
| WOS记录号 | WOS:000433957200011 |
| 出版者 | SPRINGER |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/1041]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所 |
| 作者单位 | 1.CAS MPG Partner Inst Computat Biol, Shanghai, Peoples R China; 2.Wiss Zentrum Vitroconnect Syst GmbH, Gutersloh, Germany; 3.Univ Bielefeld, Fak Math, Bielefeld, Germany, |
| 推荐引用方式 GB/T 7714 | Dress, Andreas,,. Why, so far, have epidemics always eventually petered out? Quasispecies theory suggests a (testable!) answer[J]. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS,2018,47(4):427-442. |
| APA | Dress, Andreas,&,.(2018).Why, so far, have epidemics always eventually petered out? Quasispecies theory suggests a (testable!) answer.EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS,47(4),427-442. |
| MLA | Dress, Andreas,et al."Why, so far, have epidemics always eventually petered out? Quasispecies theory suggests a (testable!) answer".EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 47.4(2018):427-442. |
入库方式： OAI收割
来源：上海营养与健康研究所
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