Signaling networks in the control of pluripotency
文献类型：期刊论文
| 作者 | Zhao, Hanzhi; Jin, Ying; , |
| 刊名 | CURRENT OPINION IN GENETICS & DEVELOPMENT
 |
| 出版日期 | 2017 |
| 卷号 | 46期号:-页码:141-148 |
| 关键词 | colitis EZH2 TNF alpha NF-kappa B ITCH |
| ISSN号 | 0959-437X |
| DOI | 10.1016/j.gde.2017.07.013 |
| 文献子类 | Review |
| 英文摘要 | Embryonic stem cells (ESCs) are characterized by their ability of unlimited self-renewal in vitro and pluripotent developmental potential, which endows them with great values in basic research and future clinical application. However, realization of full potential of ESCs is dependent on the elucidation of molecular mechanisms governing ESCs, among which signaling pathways play critical roles. A great deal of efforts has been made in the past decades to understand what and how signaling pathways contribute to the establishment and maintenance of pluripotency. In this review, we discuss signaling networks in both mouse and human ESCs, focusing on signals involved in the control of self-renewal and differentiation. In addition, the modulation of signaling pathways by pluripotency-associated transcription factors is also briefly summarized. |
| 学科主题 | Cell Biology ; Genetics & Heredity |
| WOS关键词 | EMBRYONIC STEM-CELLS ; FIBROBLAST-GROWTH-FACTOR ; GROUND-STATE PLURIPOTENCY ; MAINTAIN SELF-RENEWAL ; MOUSE ES CELLS ; WNT/BETA-CATENIN ; BETA-CATENIN ; ENDODERM DIFFERENTIATION ; DEFINITIVE ENDODERM ; NAIVE PLURIPOTENCY |
| 语种 | 英语 |
| WOS记录号 | WOS:000411955300018 |
| 出版者 | CURRENT BIOLOGY LTD |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/1098]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所 |
| 作者单位 | Shanghai Jiao Tong Univ, Sch Med, Key Lab Stem Cell Biol,CAS Ctr Excellence Mol Cel, Inst Hlth Sci,Shanghai Inst Biol Sci,Chinese Acad, Shanghai, Peoples R China, |
| 推荐引用方式 GB/T 7714 | Zhao, Hanzhi,Jin, Ying,,. Signaling networks in the control of pluripotency[J]. CURRENT OPINION IN GENETICS & DEVELOPMENT,2017,46(-):141-148. |
| APA | Zhao, Hanzhi,Jin, Ying,&,.(2017).Signaling networks in the control of pluripotency.CURRENT OPINION IN GENETICS & DEVELOPMENT,46(-),141-148. |
| MLA | Zhao, Hanzhi,et al."Signaling networks in the control of pluripotency".CURRENT OPINION IN GENETICS & DEVELOPMENT 46.-(2017):141-148. |
入库方式： OAI收割
来源：上海营养与健康研究所
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