Systemic Wound Healing Associated with local subCutaneous Mechanical Stimulation (vol 6, 39043, 2017)
文献类型：期刊论文
| 作者 | Nardini, Christine2,3,4; Devescovi, Valentina2,3; Liu, Yuanhua2,3; Zhou, Xiaoyuan2,3; Lu, Youtao2,3; Dent, Jennifer E.2,3; Liu, Yuanhua1; Dent, Jennifer E.5; , |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:-页码:46118 |
| ISSN号 | 2045-2322 |
| DOI | 10.1038/srep46118 |
| 文献子类 | Correction |
| 英文摘要 | We performed an analysis of possible mechanisms of ligand recognition in the human nose. The analysis is based on in vivo odor threshold determination and in vitro Ca2+ imaging assays with a C/Si/Ge/Sn switch strategy applied to the compounds Lilial and Bourgeonal, to differentiate between different molecular mechanisms of odorant detection. Our results suggest that odorant detection under threshold conditions is mainly based on the molecular shape, i.e. the van der Waals surface, and electrostatics of the odorants. Furthermore, we show that a single olfactory receptor type is responsible for odor detection of Bourgeonal at the threshold level in humans in vivo. Carrying out a QM analysis of vibrational energies contained in the odorants, there is no evidence for a vibration-based recognition. |
| 学科主题 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000398397300001 |
| 出版者 | NATURE PUBLISHING GROUP |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/1102]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所 |
| 作者单位 | 1.Chinese Acad Sci, Inst Pasteur Shanghai, Bioinformat Platform, Shanghai 200031, Peoples R China; 2.Shanghai Inst Biol Sci, CAS MPG Partner Inst Computat Biol, Shanghai 200031, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 4.CNR IAC Mauro Picone, Via Taurini 19, I-00185 Rome, Italy; 5.NORSAS Consultancy Ltd, Norwich NR12 8QP, Norfolk, England, |
| 推荐引用方式 GB/T 7714 | Nardini, Christine,Devescovi, Valentina,Liu, Yuanhua,et al. Systemic Wound Healing Associated with local subCutaneous Mechanical Stimulation (vol 6, 39043, 2017)[J]. SCIENTIFIC REPORTS,2017,7(-):46118. |
| APA | Nardini, Christine.,Devescovi, Valentina.,Liu, Yuanhua.,Zhou, Xiaoyuan.,Lu, Youtao.,...&,.(2017).Systemic Wound Healing Associated with local subCutaneous Mechanical Stimulation (vol 6, 39043, 2017).SCIENTIFIC REPORTS,7(-),46118. |
| MLA | Nardini, Christine,et al."Systemic Wound Healing Associated with local subCutaneous Mechanical Stimulation (vol 6, 39043, 2017)".SCIENTIFIC REPORTS 7.-(2017):46118. |
入库方式： OAI收割
来源：上海营养与健康研究所
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