microRNA and thyroid hormone signaling in cardiac and skeletal muscle
文献类型：期刊论文
| 作者 | Zhang, Duo2; Li, Yan2; Liu, Shengnan2; Ying, Hao2; Wang, Yu-cheng3; Guo, Feifan4; Zhai, Qiwei4; Jiang, Jingjing5; Ying, Hao1,6; , |
| 刊名 | CELL AND BIOSCIENCE
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:-页码:14 |
| 关键词 | Thyroid hormone miRNA Heart Skeletal muscle |
| ISSN号 | 2045-3701 |
| DOI | 10.1186/s13578-017-0141-y |
| 文献子类 | Review |
| 英文摘要 | Thyroid hormone (TH) signaling plays critical roles in the differentiation, growth, metabolism, and physiological function of all organs or tissues, including heart and skeletal muscle. Due to the significant progress in our understanding of the molecular mechanisms that underlie TH action, it's widely accepted that TH signaling is regulated at multiple levels. A growing number of discoveries suggest that microRNAs (miRNAs) act as fine-tune regulators of gene expression and adds sophisticated regulatory tiers to signaling pathways. Recently, some pioneering studies in cardiac and skeletal muscle demonstrating the interplay between miRNAs and TH signaling suggest that miRNAs might mediate and/or modulate TH signaling. This review presents recent advances involving the crosstalk between miRNAs and TH signaling and current evidence showing the importance of miRNA in TH signaling with particular emphasis on the study of muscle-specific miRNAs (myomiRs) in cardiac and skeletal muscle. Although the research of the reciprocal regulation of miRNAs and TH signaling is only at the beginning stage, it has already contributed to our current understanding of both TH action and miRNA biology. We also encourage further investigations to address the relative contributions of miRNAs in TH signaling under physiological and pathological conditions and how a group of miRNAs are coordinated to integrate into the complex hierarchical regulatory network of TH. |
| 学科主题 | Biochemistry & Molecular Biology |
| WOS关键词 | CHAIN GENE-EXPRESSION ; ANGIOTENSIN-II RECEPTOR ; FIBER-TYPE COMPOSITION ; HEART-FAILURE ; MESSENGER-RNA ; MYOCARDIAL-INFARCTION ; SARCOPLASMIC-RETICULUM ; ENERGY-METABOLISM ; MYOSIN EXPRESSION ; MOLECULAR-BASIS |
| 语种 | 英语 |
| WOS记录号 | WOS:000396782000002 |
| 出版者 | BIOMED CENTRAL LTD |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/1229]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所 |
| 作者单位 | 1.Minist Hlth, Key Lab food safety risk Assessment, Beijing, Peoples R China; 2.Univ Chinese Acad Sci, Chinese Acad Sci, Shanghai Inst Biol Sci, Key Lab food safety Res,Inst Nutr Sci, 320 Yueyang Rd, Shanghai 200031, Peoples R China; 3.Chinese Acad Sci, Shanghai Xuhui Cent Hosp, Shanghai Clin Ctr, 966 Middle Huaihai Rd, Shanghai 200031, Peoples R China; 4.Univ Chinese Acad Sci, Chinese Acad Sci, Shanghai Inst Biol Sci, Key Lab Nutr & Metab,Inst Nutr Sci, 320 Yueyang Rd, Shanghai 200031, Peoples R China; 5.Fudan Univ, Zhongshan Hosp, Dept Endocrinol & Metab, 180 Fenglin Rd, Shanghai 200032, Peoples R China; 6.Chinese Acad Sci, Inst Nutr Sci, Shanghai Inst Biol Sci, Room A1912,New Life Sci Bldg,320 Yueyang Rd, Shanghai 200031, Peoples R China, |
| 推荐引用方式 GB/T 7714 | Zhang, Duo,Li, Yan,Liu, Shengnan,et al. microRNA and thyroid hormone signaling in cardiac and skeletal muscle[J]. CELL AND BIOSCIENCE,2017,7(-):14. |
| APA | Zhang, Duo.,Li, Yan.,Liu, Shengnan.,Ying, Hao.,Wang, Yu-cheng.,...&,.(2017).microRNA and thyroid hormone signaling in cardiac and skeletal muscle.CELL AND BIOSCIENCE,7(-),14. |
| MLA | Zhang, Duo,et al."microRNA and thyroid hormone signaling in cardiac and skeletal muscle".CELL AND BIOSCIENCE 7.-(2017):14. |
入库方式： OAI收割
来源：上海营养与健康研究所
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