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The Diversity of Long Noncoding RNAs and Their Generation

文献类型：期刊论文

作者Wu, Huang1,4; Chen, Ling-Ling1,3,4; Yang, Li1; Yang, Li2,3; ,
刊名TRENDS IN GENETICS
出版日期2017
卷号33期号:8页码:540-552
ISSN号0168-9525
关键词Schizophrenia PANSS multi-scale analysis hot cluster grey matter volume pathway
DOI10.1016/j.tig.2017.05.004
文献子类Review
英文摘要Long noncoding RNAs (lncRNAs) are emerging as potential key regulators in gene expression networks and exhibit a surprising range of shapes and sizes. Several distinct classes of lncRNAs are transcribed from different DNA elements, including promoters, enhancers, and intergenic regions in eukaryotic genomes. Additionally, others are derived from long primary transcripts with noncanonical RNA processing pathways, generating new RNA species with unexpected formats. These lncRNAs can be processed by several mechanisms, including ribonuclease P (RNase P) cleavage to generate mature 30 ends, capping by small nucleolar RNA (snoRNA)-protein (snoRNP) complexes at their ends, or the formation of circular structures. Here we review current knowledge on lncRNAs and highlight the most recent discoveries of the underlying mechanisms related to their formation.
学科主题Genetics & Heredity
WOS关键词PRADER-WILLI-SYNDROME ; CIRCULAR RNAS ; GENE-EXPRESSION ; MESSENGER-RNAS ; EXON CIRCULARIZATION ; TRIPLE-HELIX ; XENOPUS-TROPICALIS ; CIRCRNA BIOGENESIS ; TRANSCRIPTION ; PROMOTERS
语种英语
CSCD记录号CSCD:30508120
出版者ELSEVIER SCIENCE LONDON
WOS记录号WOS:000405560000007
版本出版稿
源URL[http://202.127.25.144/handle/331004/1283]  
专题中国科学院上海生命科学研究院营养科学研究所
作者单位1.Univ Chinese Acad Sci, 320 Yueyang Rd, Shanghai 200031, Peoples R China;
2.Chinese Acad Sci, Shanghai Inst Biol Sci, Key Lab Computat Biol, CAS MPG Partner Inst Computat Biol, 320 Yueyang Rd, Shanghai 200031, Peoples R China;
3.ShanghaiTech Univ, Sch Life Sci & Technol, 100 Haike Rd, Shanghai 201210, Peoples R China,
4.Chinese Acad Sci, State Key Lab Mol Biol, Shanghai Key Lab Mol Androl, CAS Ctr Excellence Mol Cell Sci,Shanghai Inst Bio, 320 Yueyang Rd, Shanghai 200031, Peoples R China;
推荐引用方式
GB/T 7714		 Wu, Huang,Chen, Ling-Ling,Yang, Li,et al. The Diversity of Long Noncoding RNAs and Their Generation[J]. TRENDS IN GENETICS,2017,33(8):540-552.
APA Wu, Huang,Chen, Ling-Ling,Yang, Li,Yang, Li,&,.(2017).The Diversity of Long Noncoding RNAs and Their Generation.TRENDS IN GENETICS,33(8),540-552.
MLA Wu, Huang,et al."The Diversity of Long Noncoding RNAs and Their Generation".TRENDS IN GENETICS 33.8(2017):540-552.

入库方式： OAI收割

来源：上海营养与健康研究所

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