Antimicrobial Activity and Mechanism of Functionalized Quantum Dots
文献类型：期刊论文
| 作者 | Rajendiran, Keerthiga2; Zhao, Zizhen2; Pei, De-Sheng1 ; Fu, Ailing2
|
| 刊名 | POLYMERS
 |
| 出版日期 | 2019-10-01 |
| 卷号 | 11期号:10页码:13 |
| 关键词 | quantum dots antimicrobial efficiency multi-drug resistance reactive oxygen species (ROS) |
| DOI | 10.3390/polym11101670 |
| 通讯作者 | Pei, De-Sheng(peids@cigit.ac.cn) ; Fu, Ailing(fal@swu.edu.cn) |
| 英文摘要 | An essential characteristic of quantum dots (QDs) is their antimicrobial activity. Compared with conventional antibiotics, QDs not only possess photoluminescence properties for imaging and photodynamic therapy but also have high structural stability. To enhance their antimicrobial efficiency, QDs usually are functionalized by polymers, including poly(ethylene glycol), polyethyleneimine, and poly-l-lysine. Also, QDs conjugated with polymers, such as poly(vinylpyrrolidone) and polyvinylidene fluoride, are prepared as antimicrobial membranes. The main antimicrobial mechanisms of QDs are associated with inducing free radicals, disrupting cell walls/membranes, and arresting gene expression. The different mechanisms from traditional antibiotics allow QDs to play antimicrobial roles in multi-drug-resistant bacteria and fungi. Since the toxicity of the QDs on animal cells is relatively low, they have broad application in antimicrobial research as an effective alternative of traditional antibiotics. |
| 资助项目 | Chongqing Research Program of Basic Research and Frontier Technology[cstc2018jcyjAX0612] ; Chongqing Innovation Project for Returnees from Overseas Scholars in 2018[cx2018086] ; Chongqing Key Program of Basic Research and Advanced Exploration Project[cstc2019jcyj-zdxm0092] ; CAS Team Project of the Belt and Road ; Three Hundred Leading Talents in Scientific and Technological Innovation Program of Chongqing[CSTCCXLJRC 201714] |
| WOS研究方向 | Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000495382700139 |
| 出版者 | MDPI |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/10328]  |
| 专题 | 中国科学院重庆绿色智能技术研究院 |
| 通讯作者 | Pei, De-Sheng; Fu, Ailing |
| 作者单位 | 1.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China 2.Southwest Univ, Coll Pharmaceut Sci, Chongqing 400716, Peoples R China |
| 推荐引用方式 GB/T 7714 | Rajendiran, Keerthiga,Zhao, Zizhen,Pei, De-Sheng,et al. Antimicrobial Activity and Mechanism of Functionalized Quantum Dots[J]. POLYMERS,2019,11(10):13. |
| APA | Rajendiran, Keerthiga,Zhao, Zizhen,Pei, De-Sheng,&Fu, Ailing.(2019).Antimicrobial Activity and Mechanism of Functionalized Quantum Dots.POLYMERS,11(10),13. |
| MLA | Rajendiran, Keerthiga,et al."Antimicrobial Activity and Mechanism of Functionalized Quantum Dots".POLYMERS 11.10(2019):13. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
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