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Ethylicin Prevents Potato Late Blight by Disrupting Protein Biosynthesis of Phytophthora infestans

文献类型：期刊论文

作者Zhang, Shumin1,4; Zhang, Meiquan1; Khalid, A. Rehman2; Li, Linxuan3; Chen, Yang5; Dong, Pan1; Wang, Hanyan4; Ren, Maozhi1,3
刊名PATHOGENS
出版日期2020-04-01
卷号9期号:4页码:13
关键词Phytophthora infestans ethylicin potato late blight proteomics ribosome metabonomics protein biosynthesis
DOI10.3390/pathogens9040299
通讯作者Ren, Maozhi(renmaozhi01@caas.cn)
英文摘要Phytophthora infestans, the causal agent of potato late blight, triggered the devastating Great Irish Famine that lasted from 1845 to 1852. Today, it is still the greatest threat to the potato yield. Ethylicin is a broad-spectrum biomimetic-fungicide. However, its application in the control of Phytophthora infestans is still unknown. In this study, we investigated the effects of ethylicin on Phytophthora infestans. We found that ethylicin inhibited the mycelial growth, sporulation capacity, spore germination and virulence of Phytophthora infestans. Furthermore, the integrated analysis of proteomics and metabolomics indicates that ethylicin may inhibit peptide or protein biosynthesis by suppressing both the ribosomal function and amino acid metabolism, causing an inhibitory effect on Phytophthora infestans. These observations indicate that ethylicin may be an anti-oomycete agent that can be used to control Phytophthora infestans.
资助项目National Natural Science Foundation of China[U1804231] ; National Natural Science Foundation of China[31972469] ; National Natural Science Foundation of China[31672206] ; Science and Technology Innovation Project of Chinese Academy of Agricultural Sciences[34-IUA-02] ; North Sichuan Medical College[CBY19-QD04]
WOS研究方向Microbiology
语种英语
WOS记录号WOS:000534051600025
出版者MDPI
源URL[http://119.78.100.138/handle/2HOD01W0/11123]  
专题中国科学院重庆绿色智能技术研究院
通讯作者Ren, Maozhi
作者单位1.Chongqing Univ, Sch Life Sci, Chongqing 401331, Peoples R China
2.Univ Poonch Rawalakot AJK, Dept Plant Pathol, Rawalakot 12350, Ajk, Pakistan
3.Chinese Acad Agr Sci, Inst Urban Agr, Chengdu 610000, Peoples R China
4.North Sichuan Med Coll, Sch Basic Med Sci, Nanchong 637000, Peoples R China
5.Chinese Acad Sci, Res Ctr Atmospher Environm, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Shumin,Zhang, Meiquan,Khalid, A. Rehman,et al. Ethylicin Prevents Potato Late Blight by Disrupting Protein Biosynthesis of Phytophthora infestans[J]. PATHOGENS,2020,9(4):13.
APA Zhang, Shumin.,Zhang, Meiquan.,Khalid, A. Rehman.,Li, Linxuan.,Chen, Yang.,...&Ren, Maozhi.(2020).Ethylicin Prevents Potato Late Blight by Disrupting Protein Biosynthesis of Phytophthora infestans.PATHOGENS,9(4),13.
MLA Zhang, Shumin,et al."Ethylicin Prevents Potato Late Blight by Disrupting Protein Biosynthesis of Phytophthora infestans".PATHOGENS 9.4(2020):13.

入库方式： OAI收割

来源：重庆绿色智能技术研究院

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