Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective
文献类型：期刊论文
| 作者 | Bolarin, Joshua Adedeji1,11; Oluwatoyosi, Mercy Adaramodu2,11; Orege, Joshua Iseoluwa1,11; Ayeni, Emmanuel Ayodeji3,11; Ibrahim, Yusuf Ajibola4,11; Adeyemi, Sherif Babatunde5; Tiamiyu, Bashir Bolaji6,11; Gbadegesin, Lanre Anthony7,11; Akinyemi, Toluwanimi Oluwadara8,11; Odoh, Chuks Kenneth1,11 |
| 刊名 | INTERNATIONAL IMMUNOPHARMACOLOGY
 |
| 出版日期 | 2021 |
| 卷号 | 90页码:19 |
| 关键词 | COVID-19 Therapeutics Drug interaction Antiviral drugs Health and safety |
| ISSN号 | 1567-5769 |
| DOI | 10.1016/j.intimp.2020.107228 |
| 通讯作者 | Ayeni, Emmanuel Ayodeji(ayeniemmanuel11@mails.ucas.ac.cn) |
| 英文摘要 | The disease caused by viral pneumonia called severe acute respiratory syndrome coronavirus type-2 (SARS-CoV2) declared by the World Health Organization is a global pandemic that the world has witnessed since the last Ebola epidemic, SARS and MERS viruses. Many chemical compounds with antiviral activity are currently undergoing clinical investigation in order to find treatments for SARS-CoV-2 infected patients. On-going drug-drug interaction examinations on new, existing, and repurposed antiviral drugs are yet to provide adequate safety, toxicological, and effective monitoring protocols. This review presents an overview of direct and indirect antiviral drugs, antibiotics, and immune-stimulants used in the management of SARS-CoV-2. It also seeks to outline the recent development of drugs with anti-coronavirus effects; their mono and combination therapy in managing the disease vis -`a-vis their biological sources and chemistry. Co-administration of these drugs and their interactions were discussed to provide significant insight into how adequate monitoring of patients towards effective health management could be achieved. |
| WOS关键词 | SARS CORONAVIRUS INFECTION ; GLYCOPEPTIDE ANTIBIOTICS ; MERS-COV ; IN-VITRO ; POTENT INHIBITOR ; EBOLA-VIRUS ; CHLOROQUINE ; COLCHICINE ; COVID-19 ; RNA |
| WOS研究方向 | Immunology ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000611870100001 |
| 出版者 | ELSEVIER |
| 源URL | [http://ir.imde.ac.cn/handle/131551/55936]  |
| 专题 | 中国科学院水利部成都山地灾害与环境研究所 |
| 通讯作者 | Ayeni, Emmanuel Ayodeji |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China 2.Chinese Acad Sci, Inst Bot, Beijing, Peoples R China 3.Chinese Acad Sci, Chengdu Inst Biol, Chengdu Pmb 610041, Sichuan, Peoples R China 4.Chinese Acad Sci, Sch Chem Sci, Beijing, Peoples R China 5.Uka Tarsadia Univ, CG Bhakta Inst Biotechnol, Bardoli, Gujarat, India 6.Chinese Acad Sci, Wuhan Bot Garden, Wuhan, Peoples R China 7.Chinese Acad Sci, Inst Mt Hazards & Environm, Beijing, Peoples R China 8.Chinese Acad Sci, Shenzhen Inst Adv Technol, Shenzhen, Peoples R China 9.Chinese Acad Sci, Inst Rock & Soil Mech, Wuhan, Peoples R China 10.Chinese Acad Sci, Inst Urban Environm, Xiamen, Peoples R China |
| 推荐引用方式 GB/T 7714 | Bolarin, Joshua Adedeji,Oluwatoyosi, Mercy Adaramodu,Orege, Joshua Iseoluwa,et al. Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective[J]. INTERNATIONAL IMMUNOPHARMACOLOGY,2021,90:19. |
| APA | Bolarin, Joshua Adedeji.,Oluwatoyosi, Mercy Adaramodu.,Orege, Joshua Iseoluwa.,Ayeni, Emmanuel Ayodeji.,Ibrahim, Yusuf Ajibola.,...&Adeoye, Adenike Bernice-Eloise.(2021).Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective.INTERNATIONAL IMMUNOPHARMACOLOGY,90,19. |
| MLA | Bolarin, Joshua Adedeji,et al."Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective".INTERNATIONAL IMMUNOPHARMACOLOGY 90(2021):19. |
入库方式： OAI收割
来源：成都山地灾害与环境研究所
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