中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress

文献类型:期刊论文

作者Liang, Jun1; Liu, Jing2,3; Cheng, TingQing2,5; Song, Wencheng2,3,4,5
刊名GEOMICROBIOLOGY JOURNAL
出版日期2021-01-18
关键词Aspergillus oryzae arsenate comparative transcriptome analysis differentially expressed genes resistance mechanism
ISSN号0149-0451
DOI10.1080/01490451.2021.1877854
通讯作者Cheng, TingQing(chengtq@cmpt.ac.cn) ; Song, Wencheng(wencsong@cmpt.ac.cn)
英文摘要The molecular resistance mechanism of Aspergillus oryzae (A. oryzae) under arsenate (As(V)) stress was investigated by comparative transcriptome analysis. In total, 4911 differentially expressed genes (DEGs) of A. oryzae were detected under As(V) stress, including 2103 up-regulated genes and 2808 down-regulated genes. Genes induced by As(V) were involved in metal ion binding and transportation, redox homeostasis, efflux carrier, DNA repair, volatilization, etc. Moreover, eight genes were selected for qRT-PCR verification, and their trends were consistent with RNA-Seq analysis, which proved that RNA-Seq analysis was efficient and reliable. The results indicated that the extracellular and intracellular synergistic resistance mechanisms contributed to the improvement of A. oryzae resistance to As (V).
资助项目National Natural Science Foundation of China[21876179] ; National Natural Science Foundation of China[22006001] ; Natural Science Foundation of Universities of Anhui Province[KJ2019A0914] ; University Outstanding Young Scientific Research Talent Cultivation Program Project in Anhui Province[gxyq2020091]
WOS研究方向Environmental Sciences & Ecology ; Geology
语种英语
WOS记录号WOS:000612769900001
出版者TAYLOR & FRANCIS INC
资助机构National Natural Science Foundation of China ; Natural Science Foundation of Universities of Anhui Province ; University Outstanding Young Scientific Research Talent Cultivation Program Project in Anhui Province
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/119863]  
专题中国科学院合肥物质科学研究院
通讯作者Cheng, TingQing; Song, Wencheng
作者单位1.Anhui Univ, Jianghuai Coll, Hefei, Peoples R China
2.Chinese Acad Sci, Hefei Inst Phys Sci, Inst Hlth & Med Technol, Anhui Prov Key Lab Med Phys & Technol, Hefei, Peoples R China
3.Chinese Acad Sci, Hefei Canc Hosp, Hefei, Peoples R China
4.Soochow Univ, Collaborat Innovat Ctr Radiat Med, Jiangsu Higher Educ Inst, Suzhou, Peoples R China
5.Soochow Univ, Sch Radiol & Interdisciplinary Sci, Suzhou, Peoples R China
推荐引用方式
GB/T 7714
Liang, Jun,Liu, Jing,Cheng, TingQing,et al. Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress[J]. GEOMICROBIOLOGY JOURNAL,2021.
APA Liang, Jun,Liu, Jing,Cheng, TingQing,&Song, Wencheng.(2021).Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress.GEOMICROBIOLOGY JOURNAL.
MLA Liang, Jun,et al."Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress".GEOMICROBIOLOGY JOURNAL (2021).

入库方式: OAI收割

来源:合肥物质科学研究院

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