High-performance field-effect transistor glucose biosensors based on bimetallic Ni/Cu metal-organic frameworks
文献类型：期刊论文
| 作者 | Wang, Bingfang1,2; Luo, Yuanyuan2,3 ; Gao, Lei2,3; Liu, Bo1; Duan, Guotao1
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| 刊名 | BIOSENSORS & BIOELECTRONICS
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| 出版日期 | 2021 |
| 卷号 | 171 |
| ISSN号 | 0956-5663 |
| 关键词 | Bimetallic metal-organic framework Glucose detection Biosensor Field effect transistor In situ growth method |
| DOI | 10.1016/j.bios.2020.112736 |
| 通讯作者 | Duan, Guotao(duangt@hust.edu.cn) |
| 英文摘要 | Accurate detection of glucose is essential for the diagnosis of diabetes, wherein effective and sensitive biosensors for glucose detection are needed. Here, we fabricated a glucose sensor based on field-effect transistor (FET) with bimetallic nickel-copper metal-organic frameworks (Ni/Cu-MOFs) as its channel layers which were grown in-situ through a simple one-step hydrothermal method and modified with glucose oxidase (GOD) by using glutaraldehyde (GA) as linkers. Due to the synergistic effect of Ni ions and Cu ions in MOFs, the sensor (GOD-GA-Ni/CuMOFs-FET) showed good field effect performance and great responses to glucose through enzymatic reactions. It displayed a piecewise linear relationship in the wide range (1 mu M-20 mM), and provided high sensitivity (26.05 mu Acm(-2) mM(-1)) in the low concentration (1-100 mu M) and a low detection limit (0.51 mu M). The sensor also had these advantages of high specificity, excellent reproducibility, good short-term stability and fast response time. Especially, it is indicated that the Ni/Cu-MOFs-FETs with high performance have the potential to be available sensors, paving the way for the application of bimetallic MOFs in biosensing. |
| WOS关键词 | SENSOR ; DEVICE |
| 资助项目 | National Key R&D Program of China[2019YFB2006002] ; National Natural Science Foundation of China[11674320] ; Key Research Projects of the Frontier Science CAS[QYZDB-SSW-JSC017] |
| WOS研究方向 | Biophysics ; Biotechnology & Applied Microbiology ; Chemistry ; Electrochemistry ; Science & Technology - Other Topics |
| 语种 | 英语 |
| 出版者 | ELSEVIER ADVANCED TECHNOLOGY |
| WOS记录号 | WOS:000603554800001 |
| 资助机构 | National Key R&D Program of China ; National Natural Science Foundation of China ; Key Research Projects of the Frontier Science CAS |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/119959]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Duan, Guotao |
| 作者单位 | 1.Huazhong Univ Sci & Technol, Wuhan Natl Lab Optoelect, Sch Opt & Elect Informat, Wuhan 430074, Peoples R China 2.Chinese Acad Sci, Inst Solid State Phys, Key Lab Mat Phys, Anhui Key Lab Nanomat & Nanotechnol, Hefei 230031, Peoples R China 3.Univ Sci & Technol China, Hefei 230026, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Bingfang,Luo, Yuanyuan,Gao, Lei,et al. High-performance field-effect transistor glucose biosensors based on bimetallic Ni/Cu metal-organic frameworks[J]. BIOSENSORS & BIOELECTRONICS,2021,171. |
| APA | Wang, Bingfang,Luo, Yuanyuan,Gao, Lei,Liu, Bo,&Duan, Guotao.(2021).High-performance field-effect transistor glucose biosensors based on bimetallic Ni/Cu metal-organic frameworks.BIOSENSORS & BIOELECTRONICS,171. |
| MLA | Wang, Bingfang,et al."High-performance field-effect transistor glucose biosensors based on bimetallic Ni/Cu metal-organic frameworks".BIOSENSORS & BIOELECTRONICS 171(2021). |
入库方式： OAI收割
来源：合肥物质科学研究院
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