Quantifying lateral penumbra advantages of collimated spot-scanning beam for intensity-modulated proton therapy
文献类型：期刊论文
| 刊名 | 核技术:英文版
 |
| 出版日期 | 2019 |
| 卷号 | 030 |
| 关键词 | Lateral penumbra Patient-specific block collimator Monte Carlo Intensity-modulated proton therapy |
| ISSN号 | 1001-8042 |
| 其他题名 | Quantifying lateral penumbra advantages of collimated spot-scanning beam for intensity-modulated proton therapy |
| 英文摘要 | Intensity-modulated proton therapy(IMPT)is becoming essential for proton therapy and is under rapid development.However,for IMPT,the lateral penumbra of the spot-scanning proton beam is still an urgent issue to be solved.Patient-specific block collimators(PSBCs),which can block unnecessary doses,play a crucial role in passive scattering delivery technology but are rarely used in spot scanning.One objective of this study is to investigate the lateral penumbra variations of intensity-modulated spot scanning with and without a PSBC.For fields with varying degrees of sharpness and at varying depths in a water phantom,the lateral penumbral widths were calculated using a Monte Carlo-based dose engine from RayStation 6.The results suggest that the lateral penumbral widths can be reduced by more than 30%for uniform target volumes,regardless of whether a range-shifter is used,and that the maximum dose beyond the field edges can be reduced significantly.The results of patient cases show that the doses in organs-at-risk near the edge of the target volume decrease if a PSBC is implemented.This study demonstrates that intensity-modulated spot scanning with a PSBC can effectively reduce the lateral penumbra and block unnecessary doses and is therefore promising for clinical applications in spot-scanning proton therapy. |
| 资助项目 | [Key Program of the 13th Five-Year Plan] ; [Hefei Institutes of Physical Science of the Chinese Academy of Sciences] |
| 语种 | 中文 |
| CSCD记录号 | CSCD:6608001 |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/66479]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 推荐引用方式 GB/T 7714 | . Quantifying lateral penumbra advantages of collimated spot-scanning beam for intensity-modulated proton therapy[J]. 核技术:英文版,2019,030. |
| APA | (2019).Quantifying lateral penumbra advantages of collimated spot-scanning beam for intensity-modulated proton therapy.核技术:英文版,030. |
| MLA | "Quantifying lateral penumbra advantages of collimated spot-scanning beam for intensity-modulated proton therapy".核技术:英文版 030(2019). |
入库方式： OAI收割
来源：合肥物质科学研究院
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