The 2002 AJCC TNM classification is a better predictor of primary small cell esophageal carcinoma outcome than the VALSG staging system
文献类型：期刊论文
| 刊名 | CHINESE JOURNAL OF CANCER
 |
| 出版日期 | 2013 |
| 卷号 | 32 |
| 关键词 | NEURON-SPECIFIC ENOLASE MEMORIAL-HOSPITAL EXPERIENCE OF-THE-LITERATURE THERAPY MANAGEMENT LUNG CHEMOTHERAPY RESECTION SURVIVAL TUMOR Small cell carcinoma esophagus TNM staging chemotherapy radiotherapy esophagectomy |
| ISSN号 | 1000-467X |
| 其他题名 | The 2002 AJCC TNM classification is a better predictor of primary small cell esophageal carcinoma outcome than the VALSG staging system |
| 英文摘要 | Small cell carcinoma of the esophagus (SCCE) is a rare and aggressive malignant tumor with a poor prognosis. The optimal disease staging system and treatment approaches have not yet been defined. This study aimed to evaluate the prediction of different staging systems for prognosis and treatment options of SCCE. We retrospectively accessed the clinicopathologic characteristics, treatment strategy, and prognosis of 76 patients diagnosed with primary SCCE between 2001 and 2011. The 1-, 2-, 3-, and 5-year overall survival rates were 58%, 31%, 19%, and 13%, respectively. Univariate analysis showed that the 2002 American Joint Committee on Cancer (AJCC) tumor-node-metastasis (TNM) classification (P = 0.002), Veterans Administration Lung Study Group (VALSG) stage (P = 0.001), predisposing factors (P < 0.001), T category (P = 0.023), and M category (P < 0.001) were prognostic factors for overall survival. Multivariate analysis showed that the 2002 AJCC TNM stage (P < 0.001) was the only independent prognostic factor for survival. The value of the area under the receiver operator characteristic (ROC) curve (AUC) of the 2002 AJCC TNM staging system was larger than that of VALSG staging system with regard to predicting overall survival (0.774 vs. 0.620). None of the single treatment regimens showed any benefit for survival by Cox regression analysis. Thus, the 2002 AJCC TMN staging system improved the prediction of SCCE prognosis; however, the optimal treatment regimen for SCCE remains unclear. |
| 资助项目 | [Zhejiang Provincial Natural Science Foundation] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:4870552 |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/63520]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 推荐引用方式 GB/T 7714 | . The 2002 AJCC TNM classification is a better predictor of primary small cell esophageal carcinoma outcome than the VALSG staging system[J]. CHINESE JOURNAL OF CANCER,2013,32. |
| APA | (2013).The 2002 AJCC TNM classification is a better predictor of primary small cell esophageal carcinoma outcome than the VALSG staging system.CHINESE JOURNAL OF CANCER,32. |
| MLA | "The 2002 AJCC TNM classification is a better predictor of primary small cell esophageal carcinoma outcome than the VALSG staging system".CHINESE JOURNAL OF CANCER 32(2013). |
入库方式： OAI收割
来源：合肥物质科学研究院
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