Cohort Study on Prognosis of Patients with Metastatic Colorectal Cancer Treated with Integrated Chinese and Western Medicine
文献类型：期刊论文
| 刊名 | CHINESE JOURNAL OF INTEGRATIVE MEDICINE
 |
| 出版日期 | 2018 |
| 卷号 | 24 |
| 关键词 | cohort study metastatic colorectal cancer integrative medicine |
| ISSN号 | 1672-0415 |
| 其他题名 | Cohort Study on Prognosis of Patients with Metastatic Colorectal Cancer Treated with Integrated Chinese and Western Medicine |
| 英文摘要 | Objective: To investigate the efficacy of integrated Chinese and Western medicine (IM) in the treatment of metastatic colorectal cancer (mCRC) in a cohort study. Methods: The survival outcome of patients receiving IM was compared with that of patients receiving Western medicine alone. The study design was adopted with "continuous administration of Chinese medicine for >= 3 months" as the exposure factor. Patients who met this exposure factor were assigned to the IM cohort (Group A, 110 patients). Patients who did not meet this exposure factor were assigned to the Western medicine cohort (Group B, 225 patients). The overall survival (OS), progression-free survival (PFS), and 1st year, 2nd year, and 3rd year survival in the two cohorts were compared. Results: The median OS in Group A and B were 18 months 95% confidence interval (CI) 15-21 and 16 months (95% CI 14-18), respectively, and the median PFS in Group A and B were 6 months (95% CI 4-7) and 5 months (95% CI 4-6), respectively. No statistically significant differences were observed between the groups (P=0.186, P=0.223). Group A demonstrated significantly longer OS and PFS than Group B in the following subgroups: female patients, patients with lesions in the right half of the colon, and those who received first-line treatment (P<0.05). In the subgroup of elderly patients (age>65 years), the OS in Group A was longer than that in Group B (P<0.05). Conclusion: IM could prolong the survival of patients with mCRC. |
| 资助项目 | [National Natural Science Foundation of China] ; [Beijing Health Development Research Project] ; [Project of the Chinese Academy of Traditional Chinese Medicine] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:6282435 |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/63402]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 推荐引用方式 GB/T 7714 | . Cohort Study on Prognosis of Patients with Metastatic Colorectal Cancer Treated with Integrated Chinese and Western Medicine[J]. CHINESE JOURNAL OF INTEGRATIVE MEDICINE,2018,24. |
| APA | (2018).Cohort Study on Prognosis of Patients with Metastatic Colorectal Cancer Treated with Integrated Chinese and Western Medicine.CHINESE JOURNAL OF INTEGRATIVE MEDICINE,24. |
| MLA | "Cohort Study on Prognosis of Patients with Metastatic Colorectal Cancer Treated with Integrated Chinese and Western Medicine".CHINESE JOURNAL OF INTEGRATIVE MEDICINE 24(2018). |
入库方式： OAI收割
来源：合肥物质科学研究院
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