Treatment and prognosis of cervical cancer associated with pregnancy: analysis of 20 cases from a Chinese tumor institution
文献类型：期刊论文
| 刊名 | JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B
 |
| 出版日期 | 2015 |
| 卷号 | 16 |
| 关键词 | OF-THE-LITERATURE NEOADJUVANT CHEMOTHERAPY COMPLICATING PREGNANCY RADICAL HYSTERECTOMY STAGE-IB CARCINOMA MANAGEMENT DELAY PROGRESSION GUIDELINES Cervical cancer Pregnancy Treatment Prognosis |
| ISSN号 | 1673-1581 |
| 其他题名 | Treatment and prognosis of cervical cancer associated with pregnancy: analysis of 20 cases from a Chinese tumor institution |
| 英文摘要 | This study was designed to investigate the therapeutic approaches and prognosis for cervical cancer associated with pregnancy. Clinical information, therapeutic strategies, and follow-up results of 20 patients with cervical cancer associated with pregnancy from Jan. 2000 to June 2009 in the Zhejiang Cancer Hospital were retrospectively analyzed. The International Federation of Gynecology and Obstetrics (FIGO) stages were: in situ n=1), stage IA1 n=1), stage IB1 n=5), stage IB2 n=1), stage IIA n=8), stage IIB n=3), and stage IIIB n=1). Eight patients were in the first trimester of pregnancy, four in the second, two in the third, and six at postpartum when diagnosed. The therapeutic strategies were either single or combined modalities, including surgery, radiotherapy, and chemotherapy. Fourteen patients survived, five patients died (four of remote metastasis and one of uremia), and one patient was lost to follow-up. One newborn from a patient at stage IIA carcinoma in the third trimester with postponed therapy six weeks after diagnosis survived. Retarded fetal growth was observed in one patient receiving neoadjuvant chemotherapy and cesarean section. Out of the six postpartum patients, three underwent cesarean section and survived, whereas only one out of the three who underwent vaginal delivery survived. The remaining two died of remote metastasis. Therefore, personalized treatment is necessary for cervical cancer associated with pregnancy. Cervical cancer patients in the third trimester of pregnancy can continue the pregnancy for a short period of time. There may be potential risk for the fetus by chemotherapy during pregnancy. Cesarean section is the preferred mode of delivery for pregnant cervical cancer patients. |
| 语种 | 英语 |
| CSCD记录号 | CSCD:5435964 |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/63352]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 推荐引用方式 GB/T 7714 | . Treatment and prognosis of cervical cancer associated with pregnancy: analysis of 20 cases from a Chinese tumor institution[J]. JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B,2015,16. |
| APA | (2015).Treatment and prognosis of cervical cancer associated with pregnancy: analysis of 20 cases from a Chinese tumor institution.JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B,16. |
| MLA | "Treatment and prognosis of cervical cancer associated with pregnancy: analysis of 20 cases from a Chinese tumor institution".JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B 16(2015). |
入库方式： OAI收割
来源：合肥物质科学研究院
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