Diffusion tensor imaging and proton magnetic resonance spectroscopy in brain tumor Correlation between structure and metabolism
文献类型：期刊论文
| 刊名 | NEURAL REGENERATION RESEARCH
 |
| 出版日期 | 2013 |
| 卷号 | 8 |
| 关键词 | MR SPECTROSCOPY FRACTIONAL ANISOTROPY CORPUS-CALLOSUM MULTIPLE-SCLEROSIS GLIOMAS ABNORMALITIES MENINGIOMAS INJURY GRADE neural regeneration neuroimaging brain neoplasms magnetic resonance spectroscopy diffusion tensor imaging metabolism diffusion anisotropy edema nerve fiber extracellular space correlation analysis grants-supported paper neuroregeneration |
| ISSN号 | 1673-5374 |
| 其他题名 | Diffusion tensor imaging and proton magnetic resonance spectroscopy in brain tumor: Correlation between structure and metabolism ☆ |
| 英文摘要 | Proton magnetic resonance spectroscopy and diffusion tensor imaging are non-invasive techniques used to detect metabolites and water diffusion in vivo. Previous studies have confirmed a positive correlation of individual fractional anisotropy values with N-acetylaspartate/creatine and N-acetylaspartate/choline ratios in tumors, edema, and normal white matter. This study divided the brain parenchyma into tumor, peritumoral edema, and normal-appearing white matter according to MRI data, and analyzed the correlation of metabolites with water molecular diffusion. Results demonstrated that in normal-appearing white matter, N-acetylaspartate/creatine ratios were positively correlated with fractional anisotropy values, negatively correlated with radial diffusivities, and positively correlated with maximum eigenvalues. Maximum eigenvalues and radial diffusivities in peritumoral edema showed a negative correlation with choline, N-acetylaspartate, and creatine. Radial diffusivities in tumor demonstrated a negative correlation with choline. These data suggest that the relationship between metabolism and structure is markedly changed from normal white matter to peritumoral edema and tumor. Neural metabolism in the peritumoral edema area decreased with expanding extracellular space. The normal relationship of neural function and microstructure disappeared in the tumor region. |
| 资助项目 | [National Natural Science Foundation of China] ; [Shaanxi Provincial Scientific Research Project] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:4818390 |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/63044]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 推荐引用方式 GB/T 7714 | . Diffusion tensor imaging and proton magnetic resonance spectroscopy in brain tumor Correlation between structure and metabolism[J]. NEURAL REGENERATION RESEARCH,2013,8. |
| APA | (2013).Diffusion tensor imaging and proton magnetic resonance spectroscopy in brain tumor Correlation between structure and metabolism.NEURAL REGENERATION RESEARCH,8. |
| MLA | "Diffusion tensor imaging and proton magnetic resonance spectroscopy in brain tumor Correlation between structure and metabolism".NEURAL REGENERATION RESEARCH 8(2013). |
入库方式： OAI收割
来源：合肥物质科学研究院
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