Development of Fast Atom Bombardment Mass Spectrometry for Determination of Antioxidant Activity of Phenolic Compounds
文献类型：期刊论文
| 刊名 | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2015 |
| 卷号 | 43 |
| 关键词 | RADICAL SCAVENGING ACTIVITY HYDROXYL Antioxidant activity Fast atom bombardment mass spectrometry Molecular ion peak Phenolic compound Flavonoids |
| ISSN号 | 0253-3820 |
| 其他题名 | Development of Fast Atom Bombardment Mass Spectrometry for Determination of Antioxidant Activity of Phenolic Compounds |
| 英文摘要 | A fast atom bombardment mass spectrometric method to predict and detect the antioxidant ability of phenolic compounds was developed to accelerate the pace of finding the antioxidant with higher effect and low toxicity. The effect of experimental conditions on the relative peak intensity ratio of M+center dot ion to M+H(+) ion in the FAB mass spectra of the compound was investigated, including matrix, scan time and concentration. The correlation of antioxidant activity with the I(M+center dot)/I(M+H(+)) value of flavonoids obtained in FAB mass spectra was studied. Then the antioxidant activity of 12 phenolic compounds was predicted using the above method and the results were compared with those obtained from thiobarbituric acid (TBA) method. The results show that the I(M+center dot)/I(M+H(+)) value of the phenolic compound obtained from FAB mass spectra could reflect their antioxidant activity, which could help to accelerate the development of the antioxidant drug. |
| 资助项目 | [National Natural Science Foundation of China] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:5363203 |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/60508]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 推荐引用方式 GB/T 7714 | . Development of Fast Atom Bombardment Mass Spectrometry for Determination of Antioxidant Activity of Phenolic Compounds[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2015,43. |
| APA | (2015).Development of Fast Atom Bombardment Mass Spectrometry for Determination of Antioxidant Activity of Phenolic Compounds.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,43. |
| MLA | "Development of Fast Atom Bombardment Mass Spectrometry for Determination of Antioxidant Activity of Phenolic Compounds".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 43(2015). |
入库方式： OAI收割
来源：合肥物质科学研究院
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