Detection of ALK translocation in non-small cell lung carcinoma (NSCLC) and its clinicopathological significance using the Ventana immunohistochemical staining method: a single-center large-scale investigation of 1,504 Chinese Han patients
文献类型：期刊论文
| 刊名 | CHINESE JOURNAL OF CANCER RESEARCH
 |
| 出版日期 | 2016 |
| 卷号 | 28 |
| 关键词 | EML4-ALK FUSION CANCER ADENOCARCINOMA PCR EXPERIENCE FISH GENE Anaplastic lymphoma kinase (ALK) rearrangements fully automated immunohistochemistry (IHC) clinicopathological analysis targeted therapy |
| ISSN号 | 1000-9604 |
| 其他题名 | Detection of ALK translocation in non-small cell lung carcinoma (NSCLC) and its clinicopathological significance using the Ventana immunohistochemical staining method: a single-center large-scale investigation of 1, 504 Chinese Han patients |
| 英文摘要 | Objective: The novel fully automated immunohistochemistry (IHC) assay-Ventana anaplastic lymphoma kinase (ALK)-D5F3 for screening ALK rearrangements has been approved by China's Food and Drug Administration in 2013, our previous study disclosed a highly specificity and sensitivity nearly 100%, and its efficacy needs to be evaluated in a large cohort of primary lung adenocarcinoma patients, and to compare clinicopathological features with ALK (+) and ALK (-) lung adenocarcinoma. |
| 资助项目 | [PUMC Youth Fund] ; [Fundamental Research Funds for the Central Universities] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:5863296 |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/45524]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 推荐引用方式 GB/T 7714 | . Detection of ALK translocation in non-small cell lung carcinoma (NSCLC) and its clinicopathological significance using the Ventana immunohistochemical staining method: a single-center large-scale investigation of 1,504 Chinese Han patients[J]. CHINESE JOURNAL OF CANCER RESEARCH,2016,28. |
| APA | (2016).Detection of ALK translocation in non-small cell lung carcinoma (NSCLC) and its clinicopathological significance using the Ventana immunohistochemical staining method: a single-center large-scale investigation of 1,504 Chinese Han patients.CHINESE JOURNAL OF CANCER RESEARCH,28. |
| MLA | "Detection of ALK translocation in non-small cell lung carcinoma (NSCLC) and its clinicopathological significance using the Ventana immunohistochemical staining method: a single-center large-scale investigation of 1,504 Chinese Han patients".CHINESE JOURNAL OF CANCER RESEARCH 28(2016). |
入库方式： OAI收割
来源：合肥物质科学研究院
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