Biodegradable Zn-3Cu and Zn-3Cu-0.2Ti alloys with ultrahigh ductility and antibacterial ability for orthopedic applications
文献类型：期刊论文
| 作者 | Lin, Jixing1; Tong, Xian1,5; Wang, Kun1 ; Shi, Zimu4; Li, Yuncang3; Dargusch, Matthew2; Wen, Cuie3
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| 刊名 | JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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| 出版日期 | 2021-03-30 |
| 卷号 | 68 |
| 关键词 | Cytotoxicity Degradation behavior Mechanical properties Zn-Cu biodegradable metals |
| ISSN号 | 1005-0302 |
| DOI | 10.1016/j.jmst.2020.06.052 |
| 通讯作者 | Lin, Jixing(linjixing@163.com) ; Tong, Xian(tx847595271@163.com) ; Wen, Cuie(cuie.wen@rmit.edu.au) |
| 英文摘要 | Zinc (Zn) and its alloys have been proposed as biodegradable implant materials due to their unique combination of biodegradability, biocompatibility, and biofunctionality. However, the insufficient mechanical properties of pure Zn greatly limit its clinical application. Here, we report on the microstructure, mechanical properties, friction and wear behavior, corrosion and degradation properties, hemocompatibility, and cytocompatibility of Zn-3Cu and Zn-3Cu-0.2Ti alloys under three different conditions of as-cast (AC), hot-rolling (HR), and hot-rolling plus cold-rolling (HR + CR). The HR + CR Zn-3Cu-0.2Ti exhibited the best set of comprehensive properties among all the alloy samples, with yield strength of 211.0 MPa, ultimate strength of 271.1 MPa, and elongation of 72.1 %. Immersion tests of the Zn-3Cu and Zn-3Cu-0.2Ti alloys in Hanks' solution for 3 months indicated that the AC samples showed the lowest degradation rate, followed by the HR samples, and then the HR + CR samples, while the HR + CR Zn-3Cu exhibited the highest degradation rate of 23.9 mu m/a. Friction and wear testing of the Zn-3Cu and Zn-3Cu-0.2Ti alloys in Hanks' solution indicated that the AC samples showed the highest wear resistance, followed by the HR samples, and then the HR + CR samples, while the AC Zn-3Cu-0.2Ti showed the highest wear resistance. The diluted extracts of HR + CR Zn-3Cu and Zn-3Cu-0.2Ti at a concentration of <= 25 % exhibited noncytotoxicity. Furthermore, both the HR + CR Zn-3Cu and Zn-3Cu-0.2Ti exhibited effective antibacterial properties against S. aureus. (C) 2021 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology. |
| 资助项目 | Research Funds of the Wenzhou Science and Technology Bureau[ZG2019022] ; Research Funds of the Wenzhou Science and Technology Bureau[2018ZG008] ; Australian Research Council (ARC)[DP170102557] ; Australian Research Council (ARC)[FT160100252] ; ARC Research Hub for Advanced Manufacturing of Medical Devices[IH150100024] |
| WOS研究方向 | Materials Science ; Metallurgy & Metallurgical Engineering |
| 语种 | 英语 |
| WOS记录号 | WOS:000623854600010 |
| 出版者 | JOURNAL MATER SCI TECHNOL |
| 资助机构 | Research Funds of the Wenzhou Science and Technology Bureau ; Australian Research Council (ARC) ; ARC Research Hub for Advanced Manufacturing of Medical Devices |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/120835]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Lin, Jixing; Tong, Xian; Wen, Cuie |
| 作者单位 | 1.Zhejiang Ind & Trade Vocat Coll, Dept Mat Engn, Wenzhou 325003, Peoples R China 2.Univ Queensland, Ctr Adv Mat Proc & Mfg AMPAM, Brisbane, Qld 4072, Australia 3.RMIT Univ, Sch Engn, Melbourne, Vic 3001, Australia 4.Chinese Acad Sci, Inst Solid State Phys, Key Lab Mat Phys, Hefei 230031, Peoples R China 5.Xiangtan Univ, Sch Mat Sci & Engn, Xiangtan 411105, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin, Jixing,Tong, Xian,Wang, Kun,et al. Biodegradable Zn-3Cu and Zn-3Cu-0.2Ti alloys with ultrahigh ductility and antibacterial ability for orthopedic applications[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2021,68. |
| APA | Lin, Jixing.,Tong, Xian.,Wang, Kun.,Shi, Zimu.,Li, Yuncang.,...&Wen, Cuie.(2021).Biodegradable Zn-3Cu and Zn-3Cu-0.2Ti alloys with ultrahigh ductility and antibacterial ability for orthopedic applications.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,68. |
| MLA | Lin, Jixing,et al."Biodegradable Zn-3Cu and Zn-3Cu-0.2Ti alloys with ultrahigh ductility and antibacterial ability for orthopedic applications".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 68(2021). |
入库方式： OAI收割
来源：合肥物质科学研究院
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