Remarkable Response of Toripalimab Combined with Chemotherapy in Sarcomatoid Carcinoma of Palatine Tonsil: A Case Report
文献类型：期刊论文
| 作者 | Huang, Jiahuan2,3; Lei, Lei2,3; Chen, Bo3,4; Pan, Guoqiang5; Wang, Xiaojiao2,3; Fang, Meiyu1,3 |
| 刊名 | JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
 |
| 出版日期 | 2021 |
| 卷号 | 14 |
| 关键词 | chemotherapy combination therapy palatine tonsil cancer PD-1 inhibitor sarcomatoid carcinoma |
| ISSN号 | 1178-2390 |
| DOI | 10.2147/JMDH.S296584 |
| 通讯作者 | Wang, Xiaojiao(wxiaojia0803@163.com) ; Fang, Meiyu(fangmy@zjcc.org.cn) |
| 英文摘要 | Background: Sarcomatoid carcinoma (SaCa) of the palatine tonsil is a rare and aggressive subset of head and neck (H&N) cancer which is characterized by insensitivity to surgery and radiotherapy and a poor prognosis. Immunotherapy has led advances in the treatment of melanoma and H&N cancer, but the combined effects of immunotherapy and chemotherapy have not been sufficiently investigated. Case Presentation: Herein, we report the case of 29-year-old Chinese women with local advanced non-resectable SaCa of the palatine tonsil who exhibited a substantial partial response to toripalimab and chemotherapy followed by radiation therapy. To the best of our knowledge, this is the first report of its successful application in this context. Conclusion: Toripalimab combined with chemotherapy may be an effective approach for locally advanced H&N cancer in rare categories of patients, which was the first application as far as we know. |
| WOS关键词 | SQUAMOUS-CELL CARCINOMA ; LOCALLY ADVANCED HEAD ; NECK CANCERS ; RANDOMIZED-TRIAL ; OPEN-LABEL ; PEMBROLIZUMAB ; RECURRENT ; LARYNX ; CISPLATIN ; CETUXIMAB |
| WOS研究方向 | Health Care Sciences & Services |
| 语种 | 英语 |
| WOS记录号 | WOS:000629591600001 |
| 出版者 | DOVE MEDICAL PRESS LTD |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/121204]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Wang, Xiaojiao; Fang, Meiyu |
| 作者单位 | 1.Univ Chinese Acad Sci, Dept Med Oncol Rare Canc & Head & Neck Canc, Key Lab Head & Neck Canc Translat Res Zhejiang Pr, Zhejiang Canc Hosp,Canc Hosp, Hangzhou 310022, Peoples R China 2.Univ Chinese Acad Sci, Dept Breast Med Oncol, Zhejiang Canc Hosp, Canc Hosp, Hangzhou 310022, Peoples R China 3.Chinese Acad Sci, Inst Canc & Basic Med IBMC, Hangzhou 310022, Peoples R China 4.Univ Chinese Acad Sci, Dept Pathol, Zhejiang Canc Hosp, Canc Hosp, Hangzhou 310022, Peoples R China 5.Wenzhou Med Univ, Dept Thorac Oncol, Wenzhou 325035, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Jiahuan,Lei, Lei,Chen, Bo,et al. Remarkable Response of Toripalimab Combined with Chemotherapy in Sarcomatoid Carcinoma of Palatine Tonsil: A Case Report[J]. JOURNAL OF MULTIDISCIPLINARY HEALTHCARE,2021,14. |
| APA | Huang, Jiahuan,Lei, Lei,Chen, Bo,Pan, Guoqiang,Wang, Xiaojiao,&Fang, Meiyu.(2021).Remarkable Response of Toripalimab Combined with Chemotherapy in Sarcomatoid Carcinoma of Palatine Tonsil: A Case Report.JOURNAL OF MULTIDISCIPLINARY HEALTHCARE,14. |
| MLA | Huang, Jiahuan,et al."Remarkable Response of Toripalimab Combined with Chemotherapy in Sarcomatoid Carcinoma of Palatine Tonsil: A Case Report".JOURNAL OF MULTIDISCIPLINARY HEALTHCARE 14(2021). |
入库方式： OAI收割
来源：合肥物质科学研究院
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